Computer-aided design and construction of a novel electro-responsive ion-imprinted sensor for the individual/simultaneous detection of Cd(II) and Pb(II) in water environments.

A novel method for detecting Cd(II) and Pb(II) in water using composite ion-imprinted membranes (Cd@Pb-IIM/Ag@MOF@CHI) was developed. Pre-polymerization ratios were optimized via computer simulations and applied on Ag@MOF@CHI-modified electrodes using infrared light initiation. Characterization of the membranes through SEM and electrochemical methods revealed detailed morphology and composition.

Computer-aided design and preparation of surface arsenite molecularly imprinted polymers for selective adsorption and highly sensitive detection of As(Ⅲ).

Arsenite is a hazardous substance in water due to its high toxicity and carcinogenic nature, necessitating effective analysis and remediation methods. This study introduces surface arsenite molecularly imprinted polymers (As(Ⅲ)-MIP@MOF) and an advanced sensing platform using arsenite (H₃AsO₃) as the template. By utilizing computational simulations to optimize the functional monomer MAA and the pre-polymerization ratio, we achieved efficient arsenite removal with high adsorption capacity (328.

Application of red clover isoflavone extract as an adjuvant in mice.

In the present study, the safety of red clover isoflavone extract (RCIE) and its potential adjuvant effects on the cellular and humoral immune responses to ovalbumin (OVA) were evaluated using an ICR mouse model. On day 1, the mice were first subcutaneously immunized with 100 µg OVA, 100 µg OVA + 200 µg aluminum hydroxide gel (alum) or OVA + 50, 100 or 200 µg RCIE (RCIE + OVA), following which booster immunization was performed on day 15. After 2 weeks, the stimulation of splenocyte proliferation and levels of serum antibodies were measured.