Plasma Exosomal miRNA-139-3p is a Novel Biomarker of Colorectal Cancer.

This study investigated plasma exosomal miRNA-139-3p as a blood-based biomarker for the early diagnosis and metastasis monitoring of colorectal cancer (CRC). Exosome-rich fractions were isolated from the plasma of 80 CRC patients, and 23 controls using a kit method. We then used real-time polymerase chain reaction (RT-qPCR) to detect miR-139-3p levels in all subjects to evaluate expression levels and the predictive value of plasma exosomal miR-139-3p in CRC.

Exercise and quality of life after first-ever ischaemic stroke: a two-year follow-up study.

Background: Quality of life (QoL) post-stroke is an important health outcome. Physical deconditioning and physical inactivity are highly prevalent in stroke survivors. This study aimed to assess the long-term trends in QoL and to explore the effect of exercise on the QoL of ischaemic stroke patients.

[Changes in health-related quality of life in incipient stroke survivors].

Objective: To assess the long-term changes in quality of life of stroke patients.

Methods: A total of 467 stroke survivors were recruited for this study. The participants completed the 12-Item Short Form Health Survey (SF-12) at a three-month interval over two years.

[Assessing quality of life of patients with stroke using EQ-5D and SF-12].

Objective: To compare.the results of EQ-SD and SF-12 for assessing health-related quality of life in stroke patients.

Methods: EQ-5D and SF-12 were administered to 598 ischemic stroke patients through face-to-face interviews.