Endocrine-disrupting chemicals and breast cancer: a meta-analysis.

Background: Globally, the burden of breast cancer has increased significantly in recent decades. Emerging evidence suggested that endocrine-disrupting chemicals (EDCs), which have the potential to interfere with the function of normal hormones, may play a crucial role in this trend. However, the potential relationships were inconsistent in various studies.

Adenosine-rich extract of Ganoderma lucidum: A safe and effective lipid-lowering substance.

is a traditional Chinese medicine with a variety of active compounds and possesses adequate lipid-lowering and anti-atherosclerotic effects. However, its main active components and potential mechanisms still remain unclear. Here, we evaluated the anti-hyperlipidemic effect of the adenosine extract from (AEGL) in high-fat-diet (HFD)-induced hyperlipidemic ApoE mice and explored the underlying biological mechanism by multi-omics analysis.