Synopsis of recent research by authors named "Longchang Bai"
- Longchang Bai's recent research primarily focuses on understanding the molecular mechanisms contributing to the aggressiveness of basal-like breast cancer (BLBC), identifying specific proteins like AMD1, IMPA2, and B3GNT5 as critical factors in promoting this cancer subtype's poor prognosis and aggressive behavior
- The studies reveal that AMD1 and IMPA2 enhance tumor aggressiveness through various pathways, including the activation of MYC-driven feedback loops and the modulation of glycosylation processes, indicating potential therapeutic targets for intervention in BLBC
- Additionally, Bai's broader research interests include the investigation of natural compounds, such as polydatin and dehydrocorydaline, which exhibit anti-cancer properties, as well as exploring immunodiagnostic and therapeutic strategies for HPV-induced cancers, highlighting a diverse approach in his cancer research efforts