Publications by authors named "Longbin Shen"
Article Synopsis
- The study assessed the effectiveness of Tuina (TN) treatment alone and in combination with physiotherapy (PT) on patients with Chronic nonspecific low back pain (CNLBP) over a period from September 2020 to July 2023.
- A total of 204 participants were randomly assigned to TN, PT, or a combination of both, with significant improvements in pain levels and disability reported in all treatment groups.
- Although all groups showed improvement in primary and secondary outcomes like Visual Analog Scale (VAS) and the Oswestry Disability Index (ODI), there were no major differences between the treatments, indicating some level of equivalence in effectiveness.
Article Synopsis
- Melanoma patients often have limited responses to immunotherapies due to tumor variability, highlighting the need for effective preclinical models to study resistance and improve treatment.
- The study introduces two methods for creating melanoma patient-derived organoids (MPDOs) in collagen gel and Matrigel, which are used to evaluate immune therapies and the behavior of tumor-infiltrating lymphocytes (TILs).
- Results show that MPDOs mimic the characteristics of original melanoma tissues and can test the effectiveness of anti-PD-1 antibodies and small molecules, suggesting they are promising tools for developing new cancer therapies.
Background: The brain area stimulated during repetitive transcranial magnetic stimulation (rTMS) treatment is important in altered states of consciousness. However, the functional contribution of the M1 region during the treatment of high-frequency rTMS remains unclear.
Objective: The aim of this study was to examine the clinical [the Glasgow coma scale (GCS) and the coma recovery scale-revised (CRS-R)] and neurophysiological (EEG reactivity and SSEP) responses in vegetative state (VS) patients following traumatic brain injury (TBI) before and after a protocol of high-frequency rTMS over the M1 region.
Background: Falls are commonplace among elderly people. It is urgent to prevent falls. Previous studies have confirmed that there is a difference in plantar pressure between falls and non-falls in elderly people, but the relationship between fall risk and foot pressure has not been studied.
View Article and Find Full Text PDFObjective: Chronic nonspecific low back pain (CNLBP) is a serious medical and social problem resulting in functional decline and decreased work ability. Tuina, a form of manual therapy, has been sparsely used to treat patients with CNLBP. To systematically assess the efficacy and safety of Tuina for patients with CNLBP.
View Article and Find Full Text PDFPurpose: To evaluate the efficacy of different non-pharmacologic therapies (NPTs) on relieving depressive symptoms and pain intensity in individuals living with chronic low back pain (LBP) and associated depression.
Methods: A comprehensive search of seven English databases and two Chinese databases from inception to the search date will be undertaken. The reference lists of previously published relevant reviews and included trials will also be searched.
Novel Approach to Transfer of Coordination Skills to the Paretic Hand by Improving the Efficiency of Cortical Network.
IEEE Trans Neural Syst Rehabil Eng
April 2023
Article Synopsis
- Researchers studied if a game-like interactive system could help stroke patients improve the skills of their weaker hand by using their stronger hand and visualizing movements.
- They found that after training, both healthy people and stroke patients showed better coordination in their weaker hand and reduced interference between their hands while moving.
- The study also showed that the brain's activity became more efficient after the training, suggesting that the method could help stroke patients regain coordination in their affected hand.
By analyzing the clinical characteristics, etiological characteristics and commonly used antibiotics of patients with ventilator-associated pneumonia (VAP) in intensive care units (ICUs) in the intensive care database. This study aims to provide guidance information for the clinical rational use of drugs for patients with VAP. Patients with VAP information were collected from the Medical Information Mart for Intensive Care IV (MIMIC-IV) database, including their sociodemographic characteristics, vital signs, laboratory measurements, complications, microbiology, and antibiotic use.
View Article and Find Full Text PDFPurpose: The detection of pleural effusion in chest radiography is crucial for doctors to make timely treatment decisions for patients with chronic obstructive pulmonary disease. We used the MIMIC-CXR database to develop a deep learning model to quantify pleural effusion severity in chest radiographs.
Methods: The Medical Information Mart for Intensive Care Chest X-ray (MIMIC-CXR) dataset was divided into patients 'with' or 'without' chronic obstructive pulmonary disease (COPD).
Background: Chronic non-specific low back pain (CNLBP) is a common complaint about medical care and carries a heavy social burden. The efficacy of Tuina (TN) or physiotherapy (PT) for CNLBP has been evaluated in previous systematic reviews. However, there is no high-quality evidence to support the efficacy of Tuina.
View Article and Find Full Text PDFA novel upper-limb tracking system in a virtual environment for stroke rehabilitation.
J Neuroeng Rehabil
November 2021
Background: The transfer of the behaviors of a human's upper limbs to an avatar is widely used in the field of virtual reality rehabilitation. To perform the transfer, movement tracking technology is required. Traditionally, wearable tracking devices are used for tracking; however, these devices are expensive and cumbersome.
View Article and Find Full Text PDFBackground: Chronic nonspecific low back pain (CNLBP) is one of the most common complex pain conditions, and it is strongly associated with high rates of disability. Even though several studies on Tui na for CNLBP have been reported, to our knowledge there has been no systematic review of the currently available publications.
Objective: This study aims to develop a protocol for a systematic review and meta-analysis that will evaluate the effectiveness and safety of Tui na therapy for patients with CNLBP.
Article Synopsis
- * Nine pepper AINV genes were identified, classified into cell wall invertases and vacuolar invertases, showing similarities to AINVs in other plants.
- * Expression analyses revealed distinct patterns for two specific invertases, suggesting they are crucial for sucrose hydrolysis during the reproductive stages of pepper fruit development.
Article Synopsis
- - Alkaline/neutral invertase (NINV) proteins are crucial for breaking down sucrose into fructose and glucose and are important for plant growth, particularly during the development of pepper fruits.
- - Researchers identified seven NINV genes in peppers, classifying them into α and β groups, with one gene (CaNINV7) having missing sequences compared to others.
- - Expression analysis showed that CaNINV5 is the main enzyme involved in sucrose hydrolysis during fruit development, with its activity peaking at specific developmental stages and an optimal pH of around 7.5.
Glycine betaine (GB) accumulation is involved in abiotic stress. However, it is not known whether BADH, the key enzyme of GB synthesis, utilizes the antioxidant system to confer drought stress tolerance. In this study, a novel member of the ALDH10 gene family, SpBADH, was isolated from Sesuvium portulacastrum.
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