Efficacy and dispensing patterns of TCM-acupuncture combinations in vascular dementia treatment: a meta-analysis and data mining analysis.

Objectives: To evaluate the clinical efficacy of the combination of acupuncture and medicine for vascular dementia (VD) treatment, and to analyze and summarize the relevant association rules.

Methods: A systematic search of Chinese and English databases such as CNKI, VIP, Wanfang, Embase, PubMed, Cochrane Library, and Web of Science was performed along with a manual search to screen for randomized controlled trials that met the inclusion and exclusion criteria that were published over a period from January 1, 2000, to July 31, 2023. Literature quality assessment and meta-analysis were performed using the and RevMan 5.

[Preparation of atenolol monolithic osmotic pump tablets].

Aim: The simplified preparative method and formulation for atenolol monolithic osmotic pump tablets were investigated.

Methods: The core tablets with an indentation were compressed by the punch with a needle. Osmotic pump tablets were prepared by coating the indented tablets.

[Unitary-core osmotic pump tablet for controlled release of water-insoluble drug].

Aim: To study unitary-core osmotic pump tablet for delivering water-insoluble drug for 24 hours.

Methods: Unitary-core osmotic pump tablet was prepared using nifedipine as the model drug. The effects of various core formulation variables on drug release were studied.

[Sandwiched osmotic pump tablet for controlled release of water-insoluble drug].

Aim: To study sandwiched osmotic pump tablet for delivering water-insoluble drug for 24 hours.

Methods: Sandwiched osmotic pump tablet was prepared using nifedipine as the model drug. The effects of various formulation variables and orifice size on drug release were studied.