[CecropinA-magainin, a new hybrid antibacterial peptide against meticillin-resistant Staphylococcus aureus].

Objective: To study the mechanism of cecropinA-mangainin treatment on the meticillin-resistant Staphylococcus anreus biofilms.

Methods: The activity of the hybrid antibacterial peptide against Staphylococcus anreus was evaluated by the minimum inhibitory concentration (MIC) test and its effect on the bacteria membrane changes were observed through transmission electron microscope. The concentration of K+ of the tested bacterial liquid after interact with antibacterial peptide was detected with atomic absorption spectrometer.