Publications by Long-Yu Liu

Publications by authors named "Long-Yu Liu"

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Mannose antagonizes GSDME-mediated pyroptosis through AMPK activated by metabolite GlcNAc-6P.

Yuan-Li Ai Wei-Jia Wang Fan-Jian Liu Wei Fang Hang-Zi Chen Liu-Zheng Wu Long-Yu Liu

Cell Res

December 2023

Pyroptosis is a type of regulated cell death executed by gasdermin family members. However, how gasdermin-mediated pyroptosis is negatively regulated remains unclear. Here, we demonstrate that mannose, a hexose, inhibits GSDME-mediated pyroptosis by activating AMP-activated protein kinase (AMPK).

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