Publications by authors named "Long-Shan Xie"
Article Synopsis
- - The study investigates a gene linked to familial neonatal-infantile epilepsy and motor disorders, particularly focusing on seizures in infants triggered by feeding behaviors, especially vigorous sucking.
- - Researchers used a targeted gene panel and quantitative methods to identify genetic mutations in 45 cases of infantile convulsions, revealing a significant link between feeding changes and seizure events.
- - Findings indicate that modifying feeding behavior can help prevent seizures in infants with specific gene mutations, emphasizing the importance of awareness around feeding practices for at-risk infants.
Aims: CHD4 gene, encoding chromodomain helicase DNA-binding protein 4, is a vital gene for fetal development. In this study, we aimed to explore the association between CHD4 variants and idiopathic epilepsy.
Methods: Trios-based whole-exome sequencing was performed in a cohort of 482 patients with childhood idiopathic epilepsy.
[Damage to peripheral nerves induced by Campylobacter jejuni exotoxin].
Zhonghua Er Ke Za Zhi
December 2003
Objective: To explore the pathogenesis of the damage to peripheral nerves induced by Campylobacter jejuni exotoxin (CJT).
Methods: (1) Animal models: (1) The CJT was extracted from PEN 19-CJ and injected perineurally and intravenously to Wistar rats. (2) The sera and the supernatants of peripheral blood mononuclear cells (PBMCs), taken from the rats immunized with the CJT, were injected perineurally at sciatic nerves of experimental rats and intravenously, respectively.