[Keratoplasty in the management of Terrien's marginal degeneration].

Objective: To evaluate the efficacy and safety of keratoplasty combined with corneal foci resection in the treatment of Terrien's marginal degeneration (TMD).

Methods: In this nonrandomized retrospective case series, the records of 48 eyes from 40 patients with TMD who received keratoplasty from January 1995 to December 2005 in Zhongshan Ophthalmic Center were reviewed retrospectively. Orbscan topography examination was undertaken in 8 eyes of 8 patients and the refractive error of 9 eyes from 9 patients was tested before and after the operation.

[Preliminary clinical study of sutureless, small-incision deep lamellar endothelial keratoplasty surgery].

Objective: To investigate the surgical procedure, clinical efficacy, and the prevention and management of complications of sutureless, small-incision deep lamellar endothelial keratoplasty (DLEK).

Methods: Nine patients (nine eyes) with bullous keratopathy underwent sutureless, small-incision DLEK surgery, six of them was combined with anterior vitrectomy. Visual acuity, graft clearance, corneal curvature, astigmatism and endothelial cell density (ECD) were observed over a 3 - 5 month follow-up period.

[Management of corneo-conjunctival malignant melanoma with "no touch technique" surgical excision and corneoscleral lamellar keratoplasty].

Objective: To study the management of "no touch technique" surgical excision and corneoscleral lamellar keratoplasty in the treatment of corneo-conjunctival malignant melanoma.

Methods: Surgical excision for corneo-conjunctival malignant melanoma in six cases, from October 1989 to January 2004 in Zhongshan Ophthalmic Center, were performed. The entire tumors were removed in one piece without touching the tumor (no touch technique).

[Clinical observation of wound dehiscence after penetrating keratoplasty].

Objective: To investigate the treatment of wound dehiscence after penetrating keratoplasty and to evaluate the influence of this complication on visual outcome.

Methods: A retrospective analysis of 32 patients with wound dehiscence that undergone penetrating keratoplasty in Zhongshan Ophthalmic Center from July 1997 to June 2003 was performed. All involved eyes were undergone wound repair with or without iris excision, lensectomy, intraocular lens removal, anterior vitrectomy and stage I or stage II pars plana vitrectomy with gas or silicone oil tamponade according to variable extents of host-graft wound dehiscence in individual patient.

[The eyelid reconstruction in situ with allograft acellular dermal matrix].

Objective: To explore the clinical value of allograft acellular dermal matrix in the treatment of eyelid defects.

Methods: From November 2001 to November 2002, 10 patients (8 male and 2 female; age varied from 14 to 47) with 11 eyelids were treated by eyelid reconstruction in situ with implantation of 1 mm thick allograft acellular dermal matrix. In 11 eyelids with defects, 2 was totally defect, 8 was 2/3 defect, 1 was 1/3 defect.

[Long-term results of amniotic membrane transplantation for conjunctival surface reconstruction].

Objective: To investigate the long-term results of amniotic membrane transplantation (AMT) for conjunctival surface reconstruction after symblepharon resection and analysis the related factors.

Methods: Fifty-one cases (55 eyes) with symblepharon due to eye burns (chemical or heat) or Stevens-Johnson syndrome were selected for symblepharon resection and AMT. Ten eyes were performed within 1 year and twenty-three eyes in 1.

[A clinical study of amniotic membrane transplantation for severe eye burns at the acute stage].

Objective: To investigate the possibility of ocular surface reconstruction with amniotic membrane in the acute stage of burn injury, to compare the results using fresh and preserved amniotic membranes and to evaluate the surgical methods and their effects.

Methods: Consecutive patients of whole corneal burn above degree III with complete destruction of the limbus were divided into two groups to receive amniotic membrane transplantation (8 eyes of 8 patients with fresh amnion, 12 eyes of 11 patients with preserved one) or lamellar keratoplasty (24 eyes of 22 patients). The follow-up period was 12 to 26 months with an average of (15 +/- 2) months.

[Clinical characteristics of patients with dry eye syndrome].

Objective: To learn the clinical characteristics of patients with dry eye syndrome.

Methods: The following items were recorded in 115 patients (229 eyes) with dry eye, including symptoms, causation, systematic diseases, slit-lamp examination, tear break-up time, basal and reflex Schirmer's test, vital staining (fluorescent and rose bangle) and meibomian gland dysfunction examination. Rheumatoid factor and auto-antibody detection were performed in Sjögren's syndrome suspected patients.