Publications by authors named "Long-Qiu Cheng"
Eupafolin induces autophagy and apoptosis in B-cell non-Hodgkin lymphomas.
J Pharm Pharmacol
March 2021
Objectives: Eupafolin, an extract from Artemisia princeps, possesses multiple pharmacological activities. However, the effect of eupafolin on B-cell non-Hodgkin lymphomas is currently unknown. In this study, we report that eupafolin shows anticancer activity against B-cell non-Hodgkin lymphomas cell line, OCI-LY-3.
View Article and Find Full Text PDF[Effects of dihydroartemisinin on radiosensitivity of Raji cells].
Zhongguo Ying Yong Sheng Li Xue Za Zhi
May 2017
Objective: To study the effects of dihydroartemisinin (DHA) on radiation sensitivity of Raji cells, and explore its mechanisms.
Methods: CCK8 was used to determine the effect of DHA on cell viability of Raji cells; apoptosis, intracellular reactive oxygen speies(ROS) and mitochondrial membrane potential of Raji cells were detected by flow cytometry; and the protein expressions of protein kinase B(AKT), phospho-rylated-protein kinase B(p-AKT), Bcl-2 and Bax were determined by Western blot.
Results: The cells were randomly divided into four groups:control group, DHA(5μmol/L DHA), irradiation(IR, 4 Gy), IR+DHA group (4 Gy IR+5 μmol/L DHA).
Article Synopsis
- The study aimed to understand how the TGF-beta superfamily influences follicle growth in rat ovaries by examining the expression of Smad4 at various developmental stages.
- Smad4 protein was mainly found in the follicles, with its expression varying based on the ovary's maturation; it was prominent in early stages but less so in mature oocytes.
- RT-PCR results confirmed that Smad4 mRNA was present throughout all developmental stages, with specific changes in expression intensity related to follicle maturation.