Publications by authors named "Long-Ping Yao"
Neural Regen Res
December 2021
Article Synopsis
- The study investigates how MHC-I protein expression in dopaminergic neurons relates to Parkinson's disease, focusing on the role of oxidative stress and immune cell infiltration.
- Researchers used various techniques, including PCR and immunofluorescence, to confirm MHC-I expression in both cell and mouse models treated with neurotoxins associated with Parkinson's.
- Results showed that increased MHC-I led to more cytotoxic T cell infiltration, and reducing MHC-I expression decreased neuronal death, suggesting oxidative stress-induced MHC-I presentation contributes to neuronal degeneration in Parkinson's disease.
