Publications by authors named "Long-Long Liu"
Article Synopsis
- This study examined the link between dyslipidemia (DL) and health-related physical fitness (HPF) among 776 university staff, finding a DL prevalence of 41.77% in females and 51.49% in males, with no significant gender difference.
- Key risk factors for DL included age, male gender, glucose levels, hypertension, BMI, body fat, waist-to-height ratio (WHtR), and lipid accumulation product (LAP), while body composition measures like skeletal muscle index and grip strength did not show significant associations.
- The findings highlight that LAP and WHtR are more effective than BMI in predicting the risk of DL, indicating that fitness and body composition play vital roles in dyslipidem
Forkhead box M1 (FOXM1) is a typical proliferation‑associated transcription factor, which is overexpressed in many types of human cancer. We investigated the expression level of FOXM1 in patients with untreated acute leukemia (AL) and explored the correlation between expression levels and AL type. The relationship between the expression of the genes FOXM1 and mammalian target of rapamycin (mTOR) was determined after treatment of ML-2 cells with thiostrepton.
View Article and Find Full Text PDFOver-expression of FoxM1 is associated with adverse prognosis and FLT3-ITD in acute myeloid leukemia.
Biochem Biophys Res Commun
March 2014
Forkhead box M1 (FoxM1) drives cell cycle progression and the prevention of growth arrest and is over-expressed in many human malignancies. However, the characteristics of FoxM1 in acute myeloid leukemia (AML) are not clearly understood. We investigated the expression level of FoxM1 and analyzed the correlation of FoxM1 expression with AML patient characteristics and prognoses.
View Article and Find Full Text PDFInteraction of human genes WT1 and CML28 in leukemic cells.
J Huazhong Univ Sci Technolog Med Sci
February 2013
The molecular pathogenesis of leukemia is poorly understood. Earlier studies have shown both Wilms' tumor 1 suppressor gene (WT1) and CML28 abnormally expressed in malignant diseases of the hematopoietic system and WT1 played an important role in leukemogenesis. However, the relationship between molecular CML28 and WT1 has not been reported.
View Article and Find Full Text PDF[Expression and purification of GST-CML28 fusion protein and preparation of its polyclonal antibody].
Zhongguo Shi Yan Xue Ye Xue Za Zhi
December 2012
This study was aimed to investigate the expression of GST-CML28 in Escherichia Coli and to prepare its antibody. The constructed recombinant expression vectors CML28-pGEX-3X were transformed into Escherichia Coli BL21 under IPTG induction. The protein was abstracted from the transformers, and purified by a GSTrap FF column.
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