Publications by authors named "Long-Long Jin"
Article Synopsis
- A new series of quinoylalkyl side chains were created and then linked to ketolides using specific building blocks.
- The resulting compounds were tested for their effectiveness against both macrolide-sensitive and macrolide-resistant bacteria.
- Two specific compounds, 33b and 33e, demonstrated outstanding antibacterial activity comparable to the existing antibiotic telithromycin.
Some novel josamycin derivatives bearing an arylalkyl-type side chain were designed and synthesized. By HWE or Wittig reaction, 16-aldehyde group of josamycin analogs were converted into unsaturated carbonyl compounds. They were evaluated for their in vitro antibacterial activities against a panel of respiratory pathogens.
View Article and Find Full Text PDF