Single-cell analysis of angiotensin-converting enzyme II expression in human kidneys and bladders reveals a potential route of 2019 novel coronavirus infection.

Background: Since 2019, a novel coronavirus named 2019 novel coronavirus (2019-nCoV) has emerged worldwide. Apart from fever and respiratory complications, acute kidney injury has been observed in a few patients with coronavirus disease 2019. Furthermore, according to recent findings, the virus has been detected in urine.

Mechanism and Treatment Strategy of Osteoporosis after Transplantation.

Osteoporosis (OP) has emerged as a frequent and devastating complication of organ solid transplantation process. Bone loss after organ transplant is related to adverse effects of immunosuppressants on bone remodeling and bone quality. Many factors contribute to the pathogenesis of OP in transplanted patients.

[Surgical strategy for ectopic kidneys: analysis of 35 cases].

Objective: To explore the surgical strategy for ectopic kidney and evaluate the clinical outcomes.

Methods: From January 2000 to October 2009, 35 cases of ectopic kidney were treated surgically in our hospital. Definite diagnoses were established in all the cases by ultrasound, intravenous urography (IVU), cystoscope, CT, magnetic resonance urography (MRU) and radionuclide imaging before the surgery.

[Association of gene polymorphisms of cytokine and cytokine receptor with type III prostatitis].

Objective: To explore the role of the gene polymorphism of cytokine and cytokine receptors in the pathogenesis of type III prostatitis.

Methods: We genotyped 24 outpatients diagnosed with type III prostatitis and 51 healthy volunteer controls for the single nucleotide polymorphisms of 13 cytokines and cytokine receptors at 22 sites by Sequence Specific Primer -PCR (SSP-PCR).

Results: The patients exhibited significantly higher frequencies of the genotypes of IL-10-819 T/T (62.

[Evaluation of 126 radical cystectomy with orthotopic ileal or sigmoidocolic neobladder].

Objective: To evaluate the long-term clinical effects of orthotopic ileal or sigmoidocolic neobladder.

Methods: One hundred and twenty six patients with bladder cancer who underwent radical cystectomy and orthotopic ileal or sigmoidocolic neobladder from 1989 to 2001 were followed up, the clinical data was collected and analysed. Hautmann orthotopic ileal neobladder was performed on 84 cases and orthotopic sigmoidocolic neobladder was performed on 42 cases; Lymph node clearing during surgery was performed on 62 cases, chemotherapy and radiotherapy was performed on 64 cases after surgery.

[Slowing progression of chronic allograft nephropathy by conversion from cyclosporin A to tacrolimus].

Objective: To investigate the feasibility and safety of substituting tacrolimus(FK506) for cyclosporin A(CsA) on delaying the pace of renal dysfunction in patients with biopsy-proven chronic allograft nephropathy(CAN).

Methods: Seventy-three renal transplantation patients with CAN proved by allograft biopsy were collected in this study. Patients were randomly divided into 2 groups.