Accelerated Wound Healing in Diabetic Rat by miRNA-185-5p and Its Anti-Inflammatory Activity.

Aim: Addressing both inflammation and epithelialization during the treatment of diabetic foot ulcers is an important step, but current treatment options are limited. MiRNA has important prospects in the treatment of diabetic foot refractory wound ulcers. Previous studies have reported that miR-185-5p reduces hepatic glycogen production and fasting blood glucose levels.

Sea surface pCO in an urbanized coastal system (Jiaozhou Bay, China) during summer.

Various biogeochemical processes complicate carbon dioxide (CO) behaviour in coastal oceans. Through eight summer surveys, detailed variations in CO mechanisms in the urbanized Jiaozhou Bay, China, were analysed. During the rainless period, respiration and dissolved inorganic carbon input from treated wastewater made the northeastern region a strong CO source, while the western region with cleaner seawater was a weak source because calcium carbonate (CaCO) precipitation exceeded primary production.

Variations in dissolved inorganic carbon species in effluents from large-scale municipal wastewater treatment plants (Qingdao, China) and their potential impacts on coastal acidification.

With rapid development of global wastewater treatment plants (WWTPs), acidification and enhanced CO release in receiving waters caused by high-CO treated wastewater input have raised concerns. Insights into the variations in dissolved inorganic carbon (DIC) species in treated wastewater contribute to understanding the mechanisms of the acidification process. Here, we investigated three large-scale municipal WWTPs that discharged into the coast of Qingdao, China, for variations in effluent DIC species and their control mechanisms.

Bioinformatics analysis of differentially expressed proteins in prostate cancer based on proteomics data.

We mined the literature for proteomics data to examine the occurrence and metastasis of prostate cancer (PCa) through a bioinformatics analysis. We divided the differentially expressed proteins (DEPs) into two groups: the group consisting of PCa and benign tissues (P&b) and the group presenting both high and low PCa metastatic tendencies (H&L). In the P&b group, we found 320 DEPs, 20 of which were reported more than three times, and DES was the most commonly reported.

[Clinical research of percutaneous K-wires fixation after manipulative reduction combining with gypsum or splint fixation for treatment of the Barton fractures of aged people].

Objective: To investigate the feasibility of using percutaneous K-wires fixation after manipulative reduction combining with gypsum or splint fixation for treatment of the Barton fracture of aged people.

Methods: From June 2011 to May 2013, 91 patients with closed and fresh Barton fracture were analyzed retrospectively which information was complete. According to different methods these patients were divided into three groups: 33 patients in group A were treated by simplex fixation of gypsum or splint after manipulative reduction, including 20 males and 13 females with an average age of (63.

[Design of the reduction fixator and its clinical application in treating fracture of lesser trochanter of femur].

Objective: To discuss the clinical significance of the reduction and fixation for femoral lesser trochanteric fragment in treating the femoral comminuted intertrochanteric fractures.

Methods: From January 2012 to December 2013,32 patients with intertrochanteric fractures were treated by surgery, and self-designed reduction fixators were used in the patients for the fixation of lesser trochanter of femur. There were 11 males and 21 females, ranging in age from 45 to 81 years old with an average of 64 years old.

[Diagnosis of medial collateral ligament injury by stress X-ray and MRI of knee joint].

Objective: To study the application of stress X-ray of knee joint for the diagnosis ot medial collateral ligament injury.

Methods: From January 2008 to June 2011, 46 patients with medial collateral ligament injury were reviewed. Among the patients, 32 patients were male and 14 patients were female, ranging in age from 28 to 72 years, with an average of (49.

[Transpedicular porking and grafting for the treatment of thoracolumbar spinal fracture].

Objective: To investigate the application of transpedicular porking repositor, thread device and transpedical interbody bone grafting apparatus in the treatment of thoracolumbar spinal fracture.

Methods: From March 2008 to March 2011, 17 males and 15 females with thoracolumbar spinal fracture were treated by using self-designed transpedicular porking reposito, thread device and transpedical interbody bone grafting apparatus. The average age was 39.

[Treatment of double injuries of superior shoulder suspensory complex].

Objective: To explore operative method for the treatment of double injuries of superior shoulder suspensory complex (SSSC).

Methods: From January 2008 to March 2010,11 patients wiht SSSC injuries were treated, including 9 males and 2 females with an average age of 38 years (ranged from 20 to 47 years). The patients were treated with 4 methods as follows: 4 patients with fractures of neck of scapula combined with homolateral fracture of clavicle were treated with reconstituted plates; 2 patients with fractures of coracoid process or disruption of coracoclavicular ligament combined with the fracture of extremitas acromialis claviculae or acromioclavicular dislocation were treated with clavicular hook plates and cannulated compression screws; 3 patients with injuries of basilar part of acromial process combined with the glenoid cavity and acromioclavicular articulation were treated with reconstuction plates and clavicular hook plates; 2 patients with fractures of acromial process combined with acromioclavicular dislocation and the fracture of lateral third of clavicle were treated with small "T" plates and clavicular hook plates.

[Diagnosis and treatment of tarsometatarsal joint complex injury].

Objective: To explore the diagnosis and treatment of tarsometatarsal joint complex injury (TJC).

Methods: From January 2007 to January 2009,16 patients with tarsometatarsal joint complex injury were treated with open reduction and internal fixation. There were 12 males and 4 females, ranging in age from 21 to 45 years with an average of 34.

[Error diagnosis and inappropriate treatment for Essex-Lopresti injury in 2 cases].

Objective: To analyze the reason of error diagnosis and inappropriate treatment of radius head fractures complicating distal radioulnar joint dislocation (Essex-Lopresti injury) and to seek for the reasonable treatment.

Methods: From 2008 to 2009, 2 male patients of radius head fractures complicating distal radioulnar joint dislocation were treated, the age was 56 and 66 years old respectively. The symptom included elbow swelling and limitation of forearm rotation.

[POC content in size-fractioned TSS and transportation character in the Yellow River].

Relationship between grain size of total suspended solids (TSS) and particulate organic carbon (POC) content is the base of studying POC transportation and flux in river. Based on sedimentation classification, POC in size-fractioned TSS of The Yellow River was studied by multiple linear regression. The results indicate that: with the median diameter increasing, POC is decreased in a logarithm tendency, the maximum is 0.

[Contaminative conditions evaluation of sixteen main rivers flowing into sea around Bohai Sea, in summer of 2005].

In order to study the pollution conditions of sixteen main rivers around Bohai Sea such as Yellow River and so on, water samples were collected synchronously from July 1 to July 5 in summer of 2005. The results show that, thirteen rivers are worse than the IV water, and eight rivers such as Ziyaxinhe River and so on are worse than the V water. By analysing the sharing ratio of pollution, the key pollutant is petroleum (eleven rivers), the second is nutrients, and the third is permanganate index.

[Phenomena of pH instant increasing and its effect on dissolved inorganic carbon flux to sea in Yellow River estuary].

Dissolved inorganic carbon (DIC), pH, the partial pressure of CO (pCO2), total alkalinity (TA), dissolved oxygen saturation (DO), chlorophyll a (Chl-a), and NH4+, PO4(3-) were studied in mixing zone of Yellow River estuary from September 2004 to April 2006. The results indicate that pH value is higher than that of freshwater in low salinity area where DIC is non-conservative. NH4+, PO4(3-) sharply decreasing indicates that biogenic respiration is possibly inhibited in early mixing of freshwater and seawater, then pCO2, which is derived from biogenic respiration, swiftly decrease and lead to CaCO3 precipitation in low salinity area, and the pH value will simultaneously increase in this area.