Efficient removal of copper ions and organic dyes using chitosan, pectin, and magnetic hydrogel composites: Structural characterization and adsorption mechanisms.

This study investigates the adsorption efficiencies of twelve hydrogel groups, including chitosan, pectin, sodium alginate, cypress, bitter ginseng, dandelion, persimmon leaf, and magnetic hydrogels, for the removal of copper ions, methylene blue, and congo red from aqueous solutions. The hydrogels were characterized using SEM, XRD, XPS, BET, VSM, TGA, FTIR, and DFT calculations to elucidate their structural and functional properties. Adsorption kinetics, isotherms, and mechanisms were thoroughly analyzed, with models fitted to the experimental data.

Chemical Constituents from the deep-sea-derived Fungus Aureobasidium melanogenum LUO5.

Three new C and C aliphatic δ-lactones (1-3), three new fatty acid methyl esters (4-6), and eight known compounds (7-14) were isolated from the marine Aureobasidium sp. LUO5. Their structures were established by detailed analyses of the NMR, HRESIMS, optical rotation, and ECD data.

Penidihydrocitrinins A-C: New Polyketides from the Deep-Sea-Derived W17 and Their Anti-Inflammatory and Anti-Osteoporotic Bioactivities.

Three new polyketides (penidihydrocitrinins A-C, -) and fourteen known compounds (-) were isolated from the deep-sea-derived W17. Their structures were elucidated by comprehensive analyses of 1D and 2D NMR, HRESIMS, and ECD calculations. Compounds - were evaluated for their anti-inflammatory and anti-osteoporotic bioactivities.

Aphidicolin Chemistry of the Deep-Sea-Derived Fungus MCCC 3A00494.

Aphidicolin, a potent DNA polymerase α inhibitor, has been explored in clinical trials for the treatment of cancer. So far, about 300 modified aphidicolins have been discovered. However, none have shown a stronger effect.

Open-Ring Butenolides from a Marine-Derived Anti-Neuroinflammatory Fungus Y10.

To investigate structurally novel and anti-neuroinflammatory natural compounds from marine-derived microorganisms, the secondary metabolites of Y10, a fungus separated from the sediment of the coast in the South China Sea, were studied. Three new compounds (⁻), with novel open-ring butenolide skeletons, were isolated from the ethyl acetate extract of the culture medium. In addition, a typical new butenolide, asperteretal F (), was found to dose-dependently inhibit tumor necrosis factor (TNF-α) generation with an IC of 7.

Diastereoselective synthesis and bioactivity of long-chain anti-2-amino-3-alkanols.

An improved four-step approach for the stereoselective synthesis of long-chain anti-2-amino-3-alkanols is described. Using this method, the syntheses of antiproliferative (antitumoral) compounds, spisulosine (ES-285, 2), clavaminols A and B (3 and 4), the deacetylated products of clavaminols H and N (7 and 8), as well as (2S,3R)-2-aminododecan-3-ol (9) and xestoaminol C (10), have been achieved in excellent diastereoselectivities. In vitro study showed that these compounds induced cell death and dose-dependently inhibited cell proliferation in human glioblastoma cell line SHG-44, indicating the anti-tumor property of this series of compounds.