The decline of fertility in male uremic patients is correlated with low expression of the cystic fibrosis transmembrane conductance regulator protein (CFTR) in human sperm.

Background: The present study was designed to investigate the possible association between infertility of male uremic patients and expression of the cystic fibrosis transmembrane conductance regulator (CFTR) protein in their sperm.

Methods: Semen was collected and analyzed. Serum levels of FSH, LH and testosterone were measured by radioimmunoassay.

Timing, conditions, and complications of post-operative conception and pregnancy in female renal transplant recipients.

The aim of this study was to explore the timing, conditions, and complications of post-operative conception and pregnancy among female renal transplant recipients in China. A cohort of 25 female renal transplant recipients who subsequently had successful pregnancies was randomly selected from eight organ transplantation centers in China. In this cohort, there were 38 post-transplant conceptions and 25 live births.

Measurements of serum pituitary-gonadal hormones and investigation of sexual and reproductive functions in kidney transplant recipients.

Objective. To investigate changes in serum pituitary-gonadal hormones and restoration of sexual and reproductive functions after successful kidney transplantation. Patients and Methods.

[Impregnate occasion for male renal transplant recipients].

Objective: To explore the impregnate occasion for male renal transplant recipients.

Methods: Twenty-six male renal transplant recipients were divided into 3 groups according to the post-transplantation time and the administered dose of Cyclosporine A: 7 in Group A (less than 6 months after renal transplantation and at the dose of 4.1-6 mg/[kg x d]), 11 in Group B (6-24 months and 2.

Marital status and fertility of 185 male renal transplant recipients in China.

A questionnaire was designed to assess the effects of renal transplantation in men of reproductive age on marital status and fertility. The study sought to correlate recipients' marital status and fertility with the health of the recipients after the transplantation, the health of children they fathered after the procedure, and the functioning of the transplanted kidney. Male recipients (n = 243) who were single and of reproductive age before renal transplantation were selected from 2007 recipients of a renal transplant recorded in the authors' hospitals in China.

[Expression of integrin-linked kinase in prostate cancer and its significance].

Objective: To investigate the expression of integrin-linked kinase (ILK) in primary prostate cancer and its clinical significance.

Methods: The expression of ILK was analysed in 50 prostate cancer and 16 benign prostatic hyperplasia samples by immunohistochemical staining.

Results: The positive percentage of ILK was 46.

Morphological characteristics of spermatozoa before and after renal transplantation.

Aim: To investigate the changes of the spermatozoa ultrastructures before and after renal transplantation in uremic patients.

Methods: The sperm of five uremic patients before and after transplantation and four healthy volunteers were collected and examined by scanning electron microscopy.

Results: Abnormal spermatozoa were found in patients pre-transplantation; abnormalities included deletion of the acrosome, absence of the postacrosomal and postnuclear ring, dumbbell-like changes of the head, tail curling, and absence of the mitochondrial sheath in the mid-segment.

[Effects of different dosages of cyclosporine A on the semen parameters of renal transplant patients].

Objectives: To evaluate the effects of different dosages of cyclosporine A (CsA) on the main semen parameters and sperm morphology of the patients after renal transplantation.

Methods: The semen of 18 patients after renal transplantation treated with different dosages of CsA was analyzed and the semen parameters and sperm morphology were compared with those of 12 normal volunteers.

Results: There was not significant difference between the main parameters of the patients treated with 1.

[A comparative study of male patient's sexual function before and after kidney transplantation].

Objectives: To investigate sexual function before and after kidney transplantation in patients with chronic nephrosis.

Methods: Eighty-six male patients were divided into 3 age groups: young-age group (Group A), middle-age group(Group B) and elder-age group(Group C). Sexual function, including potency, frequency and satisfaction of intercourse before and after the sickening, and after transplantation, were recorded in each group.