An outbreak of adult measles by nosocomial transmission in a high vaccination coverage community.

Objectives: The aims of this study were to determine the mechanism of an outbreak of measles in adults and to provide scientific measures for putting forward a measles elimination program.

Methods: We performed a cross-sectional investigation during the measles outbreak to identify a possible communication link.

Results: From November 1, 2011 to January 26, 2012, the town reported 11 cases of measles in total.

Associations between hsa-miR-603 polymorphism, lifestyle-related factors and colorectal cancer risk.

Background: Accumulated studies have suggested that single nucleotide polymorphisms (SNPs) in microRNAs are associated with risk of colorectal cancer (CRC).

Objective: We tested our hypothesis that rs11014002 in hsa-miR-603 may be associated with CRC risk with a crosstalk of life-related factors.

Methods: We conducted a case-control study which included 102 CRC patients and 204 matched cancer-free controls in Xiaoshan County.

rs12904 polymorphism in the 3'UTR of EFNA1 is associated with colorectal cancer susceptibility in a Chinese population.

Accumulated evidence has indicated that Ephrin A1 (EFNA1) is associated with angiogenesis and tumorigenesis in various types of malignancies, including colorectal cancer (CRC). In the current study, we performed an online search using the public microarray database to investigate whether EFNA1 expression might be altered in CRC tissues. We then conducted a case-control study including 306 subjects (102 cases and 204 well-matched controls) in Xiaoshan County to assess any association between genetic polymorphisms in EFNA1 and CRC susceptibility.