Publications by authors named "Long-Chen Yu"
Application of as a biomarker in gastrointestinal malignancies.
World J Gastrointest Oncol
June 2024
Article Synopsis
- GI cancers are among the deadliest worldwide, making early diagnosis challenging due to their subtle onset and rapid progression, leading to poor treatment outcomes.
- A specific gram-negative, spore-free anaerobic bacterium is linked to the development of various GI cancers, including colorectal and gastric cancers, through complex mechanisms.
- Recent research indicates this bacterium could serve as a potential biomarker for GI malignancies, with its presence in stool, saliva, and serum possibly aiding in diagnosis, risk assessment, and tracking disease progression.
Colorectal cancer (CRC) is one of the most common malignancies of the digestive tract, with the annual incidence and mortality increasing consistently. Oxaliplatin-based chemotherapy is a preferred therapeutic regimen for patients with advanced CRC. However, most patients will inevitably develop resistance to oxaliplatin.
View Article and Find Full Text PDFEpidural morphine in patient-controlled analgesia regimens controls postoperative pain well but easily induces pruritus and other epidural morphine-related side effects. With 90 pregnant American Society of Anesthesiologists physical status II females scheduled for elective cesarean delivery, the present study was designed to evaluate the efficacy and safety profile of patient-controlled antipruritus (PCP) use of intravenous nalbuphine-based regimens for attenuation of postoperative pruritus and related side effects in combination with epidural morphine patient-controlled analgesia with regard to the quality of postoperative pain management. Patients were randomly assigned to two nalbuphine groups (5 μg/kg/hour, Group N5 or 10 μg/kg/hour, Group N10) and bolus dose of 1.
View Article and Find Full Text PDF