3D cross-linked structure of dual-active site CoMoO nanosheets@graphite felt electrode for vanadium redox flow battery.

Transition metal oxides (TMOs) can accelerate the sluggish kinetics of vanadium redox reaction, but face challenges like limited active sites and difficulties in nanometerization, highlighting the urgent need for new TMO electrocatalysts for vanadium redox flow battery (VRFB). CoMoO features high electrochemical activity, numerous redox sites, flexible control, and short electron pathways. Herein, a high catalytic and super stable graphite felt electrode modified in situ with network cross-linking CoMoO nanosheets (CoMoO@GF) was prepared via hydrothermal and heat treatment method to enhance VRFB performance.

Decrease in provider stigma is associated with improved quality health indicators among individuals receiving methadone in primary care centers in Ukraine.

Introduction: People who inject drugs experience poor health and social outcomes which improve with opioid agonist therapies like methadone, yet provider stigma may influence healthcare utilization. In Ukraine, integrating methadone into primary care centers (PCCs) provides an opportunity to examine provider stigma and its impact on patient outcomes.

Methods: This sub-analysis included patients randomized to receive methadone in PCCs as part of an implementation trial in which the control group received methadone in specialty addiction clinics in Ukraine.

Effect of poly(vinyl alcohol)-g-poly(lactic acid) on the oxygen barrier performance of poly(lactic acid)-based film.

In order to improve the oxygen barrier performance of poly(lactic acid) (PLA), a simple and economical melt blending method was chosen and poly(vinyl alcohol) (PVOH) with excellent oxygen barrier was used as the reinforcing phase to meet high oxygen needs. To improve compatibility, PLA was grafted onto PVOH through L-LA ring opening polymerization to get poly(vinyl alcohol)-graft-poly(lactic acid) (PVOH-g-PLA). The films with high oxygen barrier performance were prepared by blending PLA with PVOH-g-PLA.

Olaparib and Radiotherapy Induce Type I Interferon- and CD8+ T Cell-Dependent Sensitization to Immunotherapy in Pancreatic Cancer.

PARP inhibitors sensitize pancreatic ductal adenocarcinoma (PDAC) to radiation by inducing DNA damage and replication stress. These mechanisms also have the potential to enhance radiation-induced type I interferon (T1IFN)-mediated antitumoral immune responses. We hypothesized that the PARP inhibitor olaparib would also potentiate radiation-induced T1IFN to promote antitumor immune responses and sensitization of otherwise resistant PDAC to immunotherapy.

A bibliometric analysis of immunotherapy for atherosclerosis: trends and hotspots prediction.

Introduction: An increasing number of studies have demonstrated that immunotherapy may play a significant role in treating Atherosclerosis and has emerged as a promising therapy in this field. The aim of this study is to provide a comprehensive perspective through bibliometric analysis and investigate the existing hotspots and frontiers.

Methods: This study searched records from Web of Science, PubMed, and Scopus from January 1, 1999, to May 27, 2023.

Adjuvant Immunotherapy Does Not Improve Survival in Non-small Cell Lung Cancer with Major/Complete Pathological Response after Induction Immunotherapy.

Objective: In patients with resectable non-small cell lung cancer (NSCLC), immune checkpoint inhibitor (ICI)-based regimens in both neoadjuvant and perioperative settings demonstrate survival benefit. To date, no study has compared the efficacy between pure neoadjuvant and perioperative approaches, especially in patients who achieve substantial pathological responses.

Methods: In this retrospective study, patients with clinical stage II-IIIB NSCLC who achieved either major (MPR) or complete (pCR) pathological response after induction ICI plus chemotherapy followed by resection between 2019 and 2023 were identified from multicenter databases.

Clinical Characteristics and Management of Checkpoint Inhibitor Pneumonitis in Non-Small-Cell Lung Cancer Patients After Neoadjuvant Immunotherapy.

Objective: Neoadjuvant immunotherapy with checkpoint inhibitors has shown promising results for non-small-cell lung cancer (NSCLC) patients. However, it has been associated with immune-related adverse events (irAEs), including checkpoint inhibitor pneumonitis (CIP), which can be life-threatening.

Methods: This retrospective study analysed the medical records of 197 NSCLC patients who underwent neoadjuvant checkpoint inhibitor therapy to investigate the incidence, clinical characteristics, and management of CIP.

Antagonistic Effect of Nitrate Conversion on Photocatalytic Reduction of Aqueous Pertechnetate and Perrhenate.

Sustainable photocatalysis can effectively reduce the radioactive TcO to less soluble TcO·HO(s), but the reduction efficiency is highly susceptible to coexisting nitrate (NO). Here, we quantitatively investigate photocatalytic remediation conditions for Tc-contaminated water stimulated by the analogue perrhenate (ReO) in the presence of NO, and we elucidate the influence mechanism of NO by in situ characterizations. The interfering NO can compete with Re(VII) for the carbonyl radical (·CO) produced by formic acid (HCOOH) oxidation to generate nitrogen-containing products such as NH, NO, and NO, resulting in the decrease in the Re(VII) reduction ratio.

Effects of plastic film mulching on soil microbial carbon metabolic activity and functional diversity at different maize growth stages in cool, semi-arid regions.

Introduction: Plastic film mulching has been widely used to enhance soil hydrothermal conditions and increase crop yields in cool, semi-arid areas. However, its impact on soil microbial carbon metabolic activity and functional diversity during plant growth remains unclear despite their important roles in nutrient cycling and soil quality evaluation.

Methods: This study used the Biolog EcoPlate technique to investigate the dynamics and driving factors of soil microbial carbon metabolic activity and functional diversity at different maize growth stages following plastic film mulching.

Mental health disorder in chronic liver disease: a questionnaire survey.

Background: The mental health of patients with chronic liver disease (CLD) warrants greater attention and understanding, especially concerning its risk factors.

Method: Patients from our hospital's hepatology clinic were consecutively enrolled and completed a questionnaire assessing anxiety, depression, and sleep quality using the GAD-7, PHQ-9, and PSQI scales, respectively. Reliability and validity were evaluated with Cronbach's α and Kaiser-Meyer-Olkin (KMO).

Numerical Study on the Variable-Temperature Drying and Rehydration of Shiitake.

Variable-temperature convective drying (VTCD) is a promising technology for obtaining high-quality dried mushrooms, particularly when considering rehydration capacity. However, accurate numerical models for variable-temperature convective drying and rehydration of shiitake mushrooms are lacking. This study addresses this gap by employing a model with thermo-hydro and mechanical bidirectional coupling to investigate five dehydration characteristics (moisture ratio, drying rate, temperature, evaporation rate, and volume shrinkage ratio) and a drying load characteristic (enthalpy difference) during VTCD.

A Mixed-Pure Planar Heterojunction Structure of Active Layers for Efficient Sequential Blade-Coating Organic Solar Cells.

Precise modulating the vertical structure of active layers to boost charge transfer is an effective way to achieve high power conversion efficiencies (PCEs) in organic solar cells (OSCs). Herein, efficient OSCs with a well-controlled vertical structure are realized by a rapid film-forming method combining low boiling point solvent and the sequential blade-coating (SBC) technology. The results of grazing incident wide-angle X-ray scattering measurement show that the vertical component distribution is varied by changing the processing solvent.

Molecular Copper-Anthraquinone Photocatalysts for Robust Hydrogen Production.

The development of robust and inexpensive photocatalysts for H production under visible light irradiation remains a significant challenge. This study presents a series of square planar copper anthraquinone complexes (RN)CuL (R = ethyl, L = alizarin dianion (CuAA); R = -butyl, L = purpurin dianion (CuPP), (2-hydroxyanthraquinone)formamide dianion (CuAHA)) as molecular photocatalysts to achieve high long-term stability in visible-light-driven H production. These complexes are self-sensitized by the anthraquinone ligands and serve as proton reduction photocatalysts without additional photosensitizers or catalysts.

Multi-scale locality preserving projection for partial multi-view incomplete multi-label learning.

Amidst advancements in feature extraction techniques, research on multi-view multi-label classifications has attracted widespread interest in recent years. However, real-world scenarios often pose a challenge where the completeness of multiple views and labels cannot be ensured. At present, only a handful of techniques have attempted to address the complex issue of partial multi-view incomplete multi-label classification, and the majority of these approaches overlook the significance of manifold structures between instances.

Conjugated diamine cation based halide perovskitoid enables robust stability and high photodetector performance.

Low-dimensional lead halide materials have proved to be intrinsically stable semiconductor materials. However, the development of one-dimensional (1D) perovskites or perovskitoids with both robust water stability and high optoelectronic performance still faces significant challenges. Here, we report a new class of 1D (TzBIPY)PbX (X = Cl, Br, I) perovskitoids featuring a π-conjugated diamine cation (TzBIPY = 2,5-di(pyridin-4-yl)thiazolo[5,4-d]thiazole).