Publications by authors named "Long Deyong"
Article Synopsis
- The study investigates whether combining linear ablation and ethanol infusion of the vein of Marshall (EIVOM) with pulmonary vein isolation (PVI) improves maintenance of sinus rhythm in patients with persistent atrial fibrillation (AF).
- Conducted as the PROMPT-AF trial across 12 hospitals in China, it enrolled 498 patients, comparing outcomes between PVI alone and the combined approach.
- Primary outcomes focused on the rate of freedom from atrial arrhythmias without antiarrhythmic drugs within a year, with various secondary outcomes related to arrhythmia recurrence and quality of life also assessed.
Background: Early rhythm control reduces the risk of cardiovascular events in patients with atrial fibrillation (AF). Despite the superiority of catheter ablation in maintaining sinus rhythm, the knowledge gaps regarding the prognostic benefits of non-early (onset of AF ≥1 year) ablation remain.
Objective: The study aimed to describe outcomes of non-early AF in the CABANA trial.
Article Synopsis
- - The study aimed to explore the link between elevated fasting plasma glucose (FPG) levels and in-hospital cardiac arrest (IHCA) in patients with acute coronary syndrome (ACS) across 241 hospitals in China from 2014 to 2019.
- - Researchers analyzed data from over 31,700 ACS patients and found a significant non-linear relationship, indicating that FPG levels above 6.1 mmol/L were associated with a higher risk of IHCA, regardless of whether patients had diabetes.
- - The findings suggest that managing high FPG levels is crucial for reducing the risk of IHCA, with percutaneous coronary intervention showing potential benefits in lowering this risk.
Rate control plays a fundamental role in the management of atrial fibrillation (AF), but the optimal target of resting heart rate (RHR) for reducing mortality remains uncertain. This study used longitudinal follow-up RHR data to evaluate the relation between RHR and all-cause mortality. Data from the Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study were retrospectively analyzed.
View Article and Find Full Text PDFBackground: The impact of comorbidity burden on outcomes of radiofrequency catheter ablation (RFCA) for atrial fibrillation (AF) in patients with heart failure and preserved ejection fraction (HFpEF) remains unclear.
Objective: The purpose of this study was to evaluate how comorbidity burden influences the association between RFCA and cardiovascular outcomes in AF patients with HFpEF.
Methods: AF patients with HFpEF from the prospective China-AF cohort, recruited between August 2011 and December 2020, were categorized into 2 groups based CHADS-VASc score: low comorbidity burden (score ≤4) and high comorbidity burden (score >4).
Randomized Controlled Trial Comparing Training of Transseptal Puncture With or Without Intracardiac Echocardiography.
Pacing Clin Electrophysiol
December 2024
Background: Intracardiac echocardiography (ICE) has been widely used in the catheter ablation of atrial fibrillation (AF). However, the value of ICE in the training of transseptal puncture (TSP) is unclear.
Methods: ICE-Training Study was a single-center, parallel-group, unmasked, randomized controlled trial registered in ChineseClinicalTrials.
Article Synopsis
- SGLT2 inhibitors (SGLT2i) may help reduce the risk of atrial fibrillation (AF) recurrence and adverse cardiovascular outcomes in heart failure (HF) patients after AF ablation, according to a study.
- The research included 736 patients who were matched based on their use of SGLT2i, with results showing that those on SGLT2i had significantly lower AF recurrence rates (22.6% vs. 35.8%) and a reduced risk of composite cardiovascular events.
- While SGLT2i users experienced fewer cardiovascular complications, there were no significant differences in all-cause mortality or specific cardiovascular deaths between the two groups.
Morphology and location of thrombus and sludge in patients with non-valvular atrial fibrillation.
BMC Cardiovasc Disord
July 2024
Background: Stroke and thromboembolism in nonvalvular atrial fibrillation (NVAF) primarily arise from thrombi or sludge in the left atrial appendage (LAA). Comprehensive insight into the characteristics of these formations is essential for effective risk assessment and management.
Methods: We conducted a single-center retrospective observational of 176 consecutive NVAF patients with confirmed atrial/appendage thrombus or sludge determined by a pre-ablation transesophageal echocardiogram (TEE) from December 2017 to April 2019.
Introduction: The anterior and lateral position of the anterolateral papillary muscle (ALPM) has found to be reached with better catheter stability and less mechanical bumping via the transseptal (TS) compared to the retrograde aortic (RA) approach. The aim of this study is to compare the TS and RA approaches on mapping and ablation of ventricular arrhythmias (VAs) arising from ALPMs.
Methods: Thirty-two patients with ALPM-VAs undergoing mapping and ablation via the TS approach were included and compared with 31 patients via the RA approach within the same period.
Background: Although the electrocardiographic and electrophysiological properties of ventricular arrhythmias (VAs) from the vicinity of the lateral tricuspid annulus (TA) have been reported in previous studies, their precise site of origin have not been addressed.
Objective: The purpose of this study was to describe the precise origin of lateral TA-VA and the relevant anatomy.
Methods: Consecutive patients with idiopathic lateral TA-VAs were reviewed and analyzed.
Background: The association between serum potassium and atrial fibrillation (AF) recurrence after catheter ablation remains unclear.
Objective: The purpose of this study was to investigate whether preprocedural serum potassium level influences AF recurrence in patients who underwent catheter ablation.
Methods: We used data of patients with AF who underwent de novo catheter ablation from the prospective Chinese Atrial Fibrillation Registry Study.
Aims: To retrospectively compare the long-term outcomes following atrial fibrillation (AF) ablation between heart failure (HF) with preserved ejection fraction (EF) (HFpEF) and reduced/mildly reduced EF (HFr-mrEF) patients, and to identify novel predictors of adverse clinical events.
Methods: In total, 1402 AF patients with HF who underwent successful ablation were consecutively enrolled. Adverse clinical events including all-cause death, HF hospitalization, and stroke were followed up.
Background: It is still unclear whether small left ventricle (LV) is an adverse structural prognostic feature in patients with atrial fibrillation (AF).
Objectives: The purpose of this study was to evaluate the association between small LV and risk of cardiovascular events in AF population.
Methods: From the China-AF registry, 7,764 patients with AF were enrolled and divided into groups with normal, small, and large LV size based on left ventricular end-diastolic dimension (LVEDD) measurement per the American Society of Echocardiography references.
Background: The only clinically approved drug that reduces doxorubicin cardiotoxicity is dexrazoxane, but its application is limited due to the risk of secondary malignancies. So, exploring alternative effective molecules to attenuate its cardiotoxicity is crucial. Colchicine is a safe and well-tolerated drug that helps reduce the production of reactive oxygen species.
View Article and Find Full Text PDFCharacteristics of Right-Sided Accessory Pathways Associated With Right Cardiac Veins.
Circ Arrhythm Electrophysiol
May 2024
Article Synopsis
- Myocardial fibers surrounding right cardiac veins (RCVs) and their role in accessory pathways (APs) have been under-researched, leading to a study of six cases identified from a larger patient group.
- Using advanced mapping techniques, the researchers categorized the venography of RCVs into three patterns, which correlated with specific ECG characteristics.
- The study found that APs could be effectively treated, with no recurrences during follow-up, highlighting the unique features of RCV-APs and their distant atrial insertions.
Efficiency and Durability of EIVOM on Acute Reconnection After Mitral Isthmus Bidirectional Block.
JACC Clin Electrophysiol
April 2024
Background: Reconnection after mitral isthmus (MI) block with radiofrequency ablation is common.
Objectives: The aim of this study was to investigate the effects of ethanol infusion in the vein of Marshall (EIVOM) on acute reconnection after MI bidirectional block.
Methods: Patients with persistent atrial fibrillation who were scheduled to receive radiofrequency ablation for the first time were randomly assigned to the radiofrequency catheter ablation (RFCA) group (n = 44) or the EIVOM group (n = 45).
Article Synopsis
- - Ventricular diverticula are pouch-like structures that occur when heart muscle bulges outward from the inner heart lining, often causing no symptoms in patients.
- - These structures, while usually muscle-based, can lead to heart rhythm issues due to disruptions in the heart's structure.
- - The case discussed focuses on a rare right ventricular apical diverticulum (RVAD) that caused significant heart rhythm problems, successfully treated with a specialized procedure called catheter ablation, with no further issues reported afterward.
Unlabelled: The therapy of ventricular preexcitation-induced dilated cardiomyopathy in very small infants or infants with a high risk of ablation is tough and related articles are rare. Effective pharmacotherapy to suppress ventricular preexcitation is valuable.
Aims: To evaluate the effectiveness and safety of pharmacotherapy for cardiac resynchronization in infants with ventricular preexcitation-induced dilated cardiomyopathy.
Catheter ablation of atrial fibrillation in patients with left bundle branch block.
Pacing Clin Electrophysiol
April 2024
Background: Left bundle branch block (LBBB) and atrial fibrillation (AF) are commonly coexisting conditions. The impact of LBBB on catheter ablation of AF has not been well determined. This study aims to explore the long-term outcomes of patients with AF and LBBB after catheter ablation.
View Article and Find Full Text PDFEvaluation of an algorithm-guided photoplethysmography for atrial fibrillation burden using a smartwatch.
Pacing Clin Electrophysiol
April 2024
Background: Wearable devices based on the PPG algorithm can detect atrial fibrillation (AF) effectively. However, further investigation of its application on long-term, continuous monitoring of AF burden is warranted.
Method: The performance of a smartwatch with continuous photoplethysmography (PPG) and PPG-based algorithms for AF burden estimation was evaluated in a prospective study enrolling AF patients admitted to Beijing Anzhen Hospital for catheter ablation from September to November 2022.
Aims: The electrocardiographic and electrophysiological characteristics of ventricular arrhythmia (VA) arising from the intramural basal inferior septum (BIS) have not been specifically addressed to date. The aim of the current study was to characterize intramural BIS-VA and distinguish it from those with endocardial origins besides clarifying the anatomical configurations of the pyramidal space.
Methods And Results: Fifty-five consecutive patients undergoing catheter ablation of VAs from BIS were identified and divided into three groups: the left ventricular (LV)-BIS group (n = 28), right ventricular (RV)-BIS group (n = 8), and intramural group (Intra, n = 19).
Oral anti-coagulants use in Chinese hospitalized patients with atrial fibrillation.
Chin Med J (Engl)
January 2024
Article Synopsis
- Oral anticoagulants (OAC) are critical for preventing strokes in patients with atrial fibrillation (AF), but their utilization in hospitalized patients in China is suboptimal.
- In a study of over 52,000 AF patients, only 20% of high-risk individuals were taking OAC upon admission, although those who did had a lower risk of ischemic stroke.
- At discharge, OAC prescriptions increased to 45.2% for high-risk patients, and factors like rhythm control strategies were linked to higher OAC usage.
Background: Effects of intensive blood pressure (BP) control on cognitive outcomes in patients with excess orthostatic BP changes are unclear. We aimed to evaluate whether orthostatic BP changes modified the effects of BP intervention on cognitive impairment.
Methods: We analyzed 8547 participants from the Systolic Blood Pressure Intervention Trial Memory and cognition IN Decreased Hypertension.
Background: Data on the performance of risk scores in predicting mortality risk after atrial fibrillation (AF) ablations are limited.
Objectives: The purpose of this study was to investigate the associations of mortality with preablation biomarkers and evaluate the performance of age, biomarker, and clinical history (ABC)-death score in patients with AF undergoing catheter ablation.
Methods: Patients with AF undergoing catheter ablations between 2013 and 2019 in the Chinese Atrial Fibrillation Registry were enrolled.
Article Synopsis
- A study examined the impact of sodium-glucose cotransporter 2 inhibitors (SGLT2i) on atrial fibrillation (AF) recurrence after catheter ablation in patients with diabetes.
- Out of 138 patients taking SGLT2i, 26.8% experienced AF recurrence, compared to 39.3% of 387 patients not taking SGLT2i, indicating a significant reduction in recurrence among those on SGLT2i.
- The findings, supported by a meta-analysis of four studies, suggest that SGLT2i therapy is associated with a lower risk of AF recurrence post-ablation in diabetic patients.