Type of infant formula increases early weight gain and impacts energy balance: a randomized controlled trial.

Background: Millions of infants are fed breast milk substitutes, and the type of infant formula can impact weight gain patterns.

Objective: We conducted a randomized controlled trial to determine the direct impact of 2 types of infant formula (cow milk formula, CMF; extensively protein hydrolyzed formula, EHF) on growth and energy balance.

Design: A racially diverse group of formula-fed infants (n = 113) were randomly assigned to either CMF or EHF from the age of 0.