Publications by authors named "Lola Bianchi"

Introduction: Congenital Central Hypoventilation Syndrome, a rare disease caused by mutation, is associated with absent or blunted CO/H chemosensitivity due to the dysfunction of PHOX2B neurons of the retrotrapezoid nucleus. No pharmacological treatment is available. Clinical observations have reported non-systematic CO/H chemosensitivity recovery under desogestrel.

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Article Synopsis
  • The study explores how a high-protein diet (HPD) in fathers affects the metabolic health of their offspring, specifically looking at male and female Wistar rats.
  • Female offspring showed no significant difference in insulin sensitivity or glucose tolerance regardless of the father's diet, while male offspring from HPD fathers exhibited better insulin sensitivity and differing insulin secretion responses.
  • The findings suggest that paternal nutrition can have lasting, sex-specific impacts on the metabolic health of offspring, emphasizing the need to consider father’s diet in discussions about developmental health.
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