[Clinic and functional features of chronic obstructive pulmonary disease after virus-induced acute exacerbations.].

Aim: To establish symptoms, lung function and to evaluate subsequent exacerbations of chronic obstructive pulmonary disease (COPD) during a year after virus-induced COPD exacerbations.

Materials And Methods: Patients hospitalized with viral (=60), bacterial (=60) and viral-bacterial (=60) COPD exacerbations were enrolled to single-center prospective observational study. COPD was diagnosed according spirography criteria.

Efficacy of 13-valent pneumococcal conjugate vaccine in healthcare workers.

Aim: To establish the efficacy of 13-valent pneumococcal conjugate vaccine (PCV13) for healthcare workers protection from occupational acquired infection and impact of healthcare staff vaccination on the risk of transmission to patients.

Materials And Methods: Healthcare personnel (n=157 of whom 105 critical care department staff) and 1770 patients of that critical care department observed. Healthcare workers received PCV13.

[General anesthesia and intensive care for patients surgically treated for deep neck odontogenic infections].

The study objectives were to determine the significance of deep neck odontogenic infections severity to predict the postoperative morbidity. Observational study was conducted in 2014-2015. A continuous sample of 38 patients who were urgently hospitalized in the Novosibirsk Regional Clinical Hospital with deep neck odontogenic infections and operated on the day of hospitalization was analyzed.

[Experience With Serelaksin for Acute Right Ventricular Failure due to Pulmonary Embolism in Acute Ischemic Stroke].

to demonstrate effects of serelaxin in treatment of acute right ventricular failure (ARVF) caused by pulmonary embolism (PE).

[The experience of submental intubation for severe maxillofacial injuries].

Oral and nasal routes for intubation are often not feasible in maxillofacial fractures. The paper presents our experience of midline and paramedial approaches for submental intubation in the airway management of facial trauma patients. The prospective study included 47 patients with maxillofacial trauma in whom submental orotracheal intubation was performed in 2005-2014.

[Effect of acute and chronic alcoholic intoxication on immunological status of patients with generalized peritonitis in the course of therapy].

Generalized peritonitis is one of the most adequate clinical models of inflammatory processes with pronounced polyorgan insufficiency in which immunological reactivity may be substantially modified by any intoxicant of exogenous origin, e.g., alcohol.

[Acute and chronic alcoholic intoxication as a cause of modified immunological reactivity in patients with generalized peritonitis].

The importance of assessment of immunological reactivity in patients with generalized peritonitis suffering alcoholic intoxication ensues from the possibility to use it for the prediction of abdominal inflammation dynamics and thereby for the optimization of organ-protective therapy in critical situations.

[Correction of endotoxicosis in alcoholic pancreatitis in elderly and senile patients using discrete plasmapheresis].

The majority of critical conditions in man occur in diseases accompanied with development of endogenic intoxication syndrome. The search for universal criterion and design of highly effective programs for correction of this condition are of great importance for internal medicine and surgical practice. Discrete plasmapheresis for endotoxicosis in elderly and gerontological patients has its specific features which should be taken into consideration because of low adaptation abilities of such group of patients.