Histochemical and morphological changes in various regions of the rat hippocampus in swimming-induced stress.

Swimming stress increased the functional activity of hippocampal pyramidal neurons in rats, as indicated by decreases in their glycogen contents and increases in their nucleic acid contents and the nucleus:cytoplasm ratio. These changes were most marked in hippocampal field CA1, while changes in other regions of the hippocampus were minimal.

[Histochemical and morphometric evidence of the participation of dorsal hippocampal neurons in the antistress effect of melatonin].

The epiphyseal hormone melatonin (0.1 mg/kg) does not influence the functional state of pyramidal neurons in the dorsal hippocamp of intact rats, but decreases the swimming-stress-induced activation of these neurons. Removal of the pineal gland increased the functional activity of neurons in the intact rats and potentiated the stress-induced histochemical and morphometric changes.

[Swimming stress-induced histochemical and morphological changes in various regions of the rat hippocampus].

In rats, swimming stress enhanced functional activity of the hippocampus' pyramidal neurones as manifested by diminishing of the glycogen contents, increasing amount of nucleic acids, augmented nucleus/cytoplasm ratio.

[Effect of diazepam on the metabolic and morphometric parameters of neurons in the dorsal hippocampus in normal and stressed rats].

Diazepam (0.5 mg/kg) decreases the swimming-stress-induced activation of the pyramidal neurons in the dorsal hippocamp. This is manifested by a decrease in the stress-induced glycogen consumption, an increase in the RNA content, and (less pronounced) increased in the nucleocytoplasmic ratio.

[The functional metabolic activity of the blood neutrophils in different clinical forms of brucellosis].

The characteristics of the activity of alkaline phosphatase, nonspecific esterase, myeloperoxidase, lysosomal cation proteins, lipids have been determined in the cytochemical study of neutrophils in peripheral blood samples of 127 patients with acute, chronic, primary chronic brucellosis and osteochondrosis. It is expedient to use these characteristics as additional tests for the differential diagnostics of different clinical forms of brucellosis, as well as residual brucellosis and osteochondrosis.

[A method for the surgical treatment of mandibular condyle fractures with dislocation of the head of the mandible].

A new method for surgical treatment of fractures of the condylar processes of the mandible with dislocation of the joint head is proposed. It consists in vertical osteotomy of the jaw branch, removal of fragments of the branch and joint head from the wound, intraosseous securing of fragments with a needle outside the operative wound, and fixation of the replant to the branch with 1 or 2 wire sutures. Sixteen patients were operated using this method, the outcomes were favorable.

[Natural resistance factors in brucellosis].

A higher level of the opsono-cytophagous capacity of the blood and the quantitative content of lysosomal cationic proteins in polymorphonuclear neutrophils in the blood of Fischer rats in comparison with the corresponding characteristics in normal guinea pigs has proved to be conductive to more active elimination of the infective agent from the body of the animals after their infection with brucellosis. The indices characterizing the activity and intensity of the phagocytosis of brucellae by polymorphonuclear neutrophils of the blood in combination with the determination of the amount of cationic proteins in these cells permit the objective characterization of the level of nonspecific resistance to brucellosis.

[Cytochemical changes in the peripheral blood leukocytes of guinea pigs inoculated against plague, tularemia and anthrax].

The immunization of guinea pigs with trivaccine and monovaccines against plaque, tularemia and anthrax induces a decrease in the activity of acidic phosphatase in lymphocytes, as well as a decrease in the number of lymphocytes containing this enzyme. A decrease in the activity of alkaline phosphatase and peroxidase had been found to occur in neutrophil leukocytes. Besides, neutrophil leukocytes have shown an increase in the activity of acidic phosphatase and nonspecific esterases.

[Comparative cytoenzymatic study of infectious and vaccinal processes in experimental brucellosis].

In experiments on 240 guinea-pigs metabolic changes were found to occur in peripheral blood cells in the process of the development of brucellosis infection and after immunization. The degree and character of the activity of lysosomal enzymes depended on the time of infection and immunity formation. In comparison with the vaccinal culture of Br.

[Disinfecting effect of fixatives in histoenzymatic analysis of Vibrio cholerae].

Data are presented on the disinfecting action of fixative fluids on the cholera causative agents in the freshly frozen sections from the tissues and organs of animals infected with cholera. The results obtained offered a possibility of drawing a conclusion on the harmlessness of the histoenzymatic studies on the material infected with cholera vibrio.

[Use of Kiel bone in plastic surgery of jaw defects].

A 5-year clinical experience with the use of Kiel bone in different osteoplastic operations on jaws in 67 patients is described. The implants proved to be effective in replacement of defects not associated with an impairment of the jaw bone integrity. Infection of the bed tissues was considered to be contraindication to implantation.