Publications by authors named "Lok Ching Sandra Chiu"
Article Synopsis
- Postoperative delirium (POD) and cognitive dysfunction (POCD) are significant complications after surgery that can lead to serious health issues; this study aimed to see if pre-surgery cognitive training helps reduce these risks.
- The analysis included seven randomized controlled trials with 864 participants, showcasing a moderate quality of reporting on cognitive training interventions, which were mostly home-based and computer-focused, lasting 2.3-10 hours over a few weeks.
- Results indicated that cognitive prehabilitation did not significantly decrease the incidence of POD or early POCD compared to standard care, but the study suggested that the sample sizes may be too small to definitively rule out any potential benefits.
Background: Sepsis surveillance using electronic health record (EHR)-based data may provide more accurate epidemiologic estimates than administrative data, but experience with this approach to estimate population-level sepsis burden is lacking.
Methods: This was a retrospective cohort study including all adults admitted to publicly-funded hospitals in Hong Kong between 2009-2018. Sepsis was defined as clinical evidence of presumed infection (clinical cultures and treatment with antibiotics) and concurrent acute organ dysfunction (≥2 point increase in baseline SOFA score).
Introduction: Protein malnutrition is associated with higher risks of postoperative complications, mortality, prolonged postoperative stays in hospital, slower physical and mental recovery after surgery and lower subsequent health-related quality of life. To reduce the risk of postoperative morbidity and mortality, nutritional prehabilitation programmes have been developed recently to build up patient's nutritional reserve to withstand the stress of surgery. The intervention involves nutritional screening and counselling, and increasing dietary protein intake in protein-malnourished patients in the several weeks before surgery.
View Article and Find Full Text PDFLongitudinal studies on upper respiratory tract microbiome in coronavirus disease 2019 (COVID-19) without potential confounders such as antimicrobial therapy are limited. The objective of this study is to assess for longitudinal changes in the upper respiratory microbiome, its association with disease severity, and potential confounders in adult hospitalized patients with COVID-19. Serial nasopharyngeal and throat swabs (NPSTSs) were taken for 16S rRNA gene amplicon sequencing from adults hospitalized for COVID-19.
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