Lacrimal myoepithelial carcinoma ex recurrent pleomorphic adenoma: A clinicopathological report and review of the literature.

Myoepithelial carcinoma is an uncommon malignant tumor of the lacrimal gland, composed of neoplastic myoepithelial cells with an infiltrative growth. The present study describes a unique case of progressive proptosis and blindness of the right eye in a 68-year-old woman following total tumor removal for lacrimal pleomorphic adenoma. Clinical study, surgical exploration, and pathology revealed lacrimal myoepithelial carcinoma ex recurrent pleomorphic adenoma, T2N0M0.

Polymorphous low-grade adenocarcinoma of the epiglottis: A case report.

Polymorphous low-grade adenocarcinoma is an uncommon malignant tumor derived from the terminal duct cells of the salivary glands. The present study described a rare case of polymorphous low-grade adenocarcinoma, T2N0M0 stage 2, in a 65-year-old man, who presented with a sore throat and painful dysphagia. Computed tomography revealed an infiltrative heterogenous enhancing mass involving the left aryepiglottic fold.

CT perfusion in predicting treatment response of nasopharyngeal carcinoma.

Background: Direct nasopharyngoscope with biopsy is the gold standard for assessing tumor response of nasopharyngeal carcinoma (NPC). It is invasive with risk of hemorrhage or infection.

Objective: Explore the usefulness of pre-treatment CTperfusion (CTP) and clarify the parameters in predicting the treatment response.

Proton magnetic resonance spectroscopy in mild cognitive impairment and Alzheimer's disease: a preliminary study.

Background: Mild cognitive impairment (MCI) is recognized as a transitional clinical state between normal aging and Alzheimer's disease (AD) and has significant higher rate of progression to AD.

Objective: To compare the changes of metabolites between AD and MCI in specific locations of the brain by using Magnetic Resonance Spectroscopy (MRS).

Material And Method: MMSE-Thai 2002 and neuropsychological test were performed in 17 patients with memory problem, classified into AD and MCI (10, 7 patients respectively).

Identification of stroke mimics among clinically diagnosed acute strokes.

Background: Stroke is a clinically syndrome of a sudden onset of neurological deficit in a vascular cause. Stroke mimics is the non-vascular disorders with stroke-like clinical symptoms. It is important to distinguish true stroke from mimics since treatment plan may differ

Objective: To determine the incidence of the stroke mimics and identify their etiologies.

Apparent diffusion coefficients in evaluation of pediatric brain tumors.

Background: MRI, which has high sensitivity in brain tumor detection, cannot reliably determine tumor grading or histology. Diffusion-weighted imaging and apparent diffusion coefficients (ADCs) provide information of tumor cellularity that can correlate with grading.

Objective: To investigate ADCs in differentiation low-grade from high-grade pediatric brain tumors.

Plasticity of the motor cortex in patients with brain tumors and arteriovenous malformations: a functional MR study.

Objective: Test the hypothesis about the potential role of functional MRI (fMRI) to evaluate the plasticity of the cortical motor areas in patients with brains tumors and brain arteriovenous malformations (AVMs) and measurement of the lesion-to-fMRI activation distance for predicting risk of new motor deficit after surgery.

Material And Method: This was a retrospective study. The present study population enrolled eight patients with motor cortex lesions.

Nasopharyngeal carcinoma segmentation using a region growing technique.

Purpose: This paper proposes a new image segmentation technique for identifying nasopharyngeal tumor regions in CT images. The technique is modified from the seeded region growing (SRG) approach that is simple but sensitive to image intensity of the initial seed.

Methods: CT images of patients with nasopharyngeal carcinoma (NPC) were collected from Ramathibodi hospital, Thailand.

Antiphospholid antibody syndrome and Hb E/Beta thalassemia disease post-allogeneic stem cell transplantation.

We report a 10-year-old male with Hb E/Beta thalassemia disease who developed chronic graft-versus-host disease (cGVHD) of antiphospholipid antibody syndrome after successful allogeneic stem cell transplantation (SCT). He exhibited a recurrent ischemic stroke on day 368 post-SCT while on cyclosporine A, azathioprine, and prednisolone. The immunosuppressive agents were switched to pulse methylprednisolone, tacolimus, mycophenolate mofetil, and enoxaparin, but the patient was more confused.

Concurrent radiotherapy with temozolomide followed by adjuvant temozolomide and cis-retinoic acid in children with diffuse intrinsic pontine glioma.

The prognosis of children with diffuse intrinsic pontine glioma (DIPG) is very poor. Radiotherapy remains the standard treatment for these patients, but the median survival time is only 9 months. Currently, the use of concurrent radiotherapy with temozolomide (TMZ) has become the standard care for adult patients with malignant gliomas.

Acute Marchiafava-Bignami disease with callosal, cortical, and white matter involvement.

Marchiafava-Bignami disease (MBD) is a rare complication of chronic alcoholism whose main pathology is symmetrical demyelination and necrosis of the corpus callous. The lesion may be found in hemispheric white matter, but the cortical involvement is extremely rare. We reported herein two cases of MBD with magnetic resonance (MR) findings, additional MR spectroscopy, and MR perfusion which revealed acute demyelination at the corpus callosum and symmetrical signal abnormality at cortical gray matter and hemispheric white matter.

Giant cell reparative granuloma concurrent with squamous cell carcinoma of the temporal bone: a case report and review of the literature.

A case of giant cell reparative granuloma concurrent with squamous cell carcinoma of the right temporal bone in a 44-year-old man with clinically presenting otorrhea from the mass of the right acoustic canal with hearing loss is reported. The histopathological examination of the lesion characterizes by multinucleated giant cells with in a fibroblastic stroma and area of keratinizing squamous cell carcinoma. GCRG may have been a local reaction provoked by the squamous cell carcinoma.

Stereotactic radiation therapy for optic nerve sheath meningioma; an experience at Ramathibodi Hospital.

Objective: To evaluate results of stereotactic radiotherapy for the treatment of optic nerve sheath meningioma (OM) at Ramathibodi Hospital.

Material And Method: Twelve patients with primary OM were treated with stereotactic radiation between 1998 and 2005. Five patients underwent surgery and had no light perception before radiation.

Favorable response of intraommaya topotecan for leptomeningeal metastasis of neuroblastoma after intravenous route failure.

A 3-year-old male, diagnosed with stage 4 neuroblastoma, developed recurrent leptomeningeal metastasis after multi-modality treatment including multi-agent chemotherapy, surgery, high dose chemotherapy plus stem cell rescue, cis-retinoic acid and intravenous (IV) topotecan. He then received intraommaya (IO) topotecan three times weekly (maximum dose; 0.4 mg).

Evaluation of MR cisternography in diagnosis of cerebrospinal fluid fistula.

Purpose: To study the clinical usefulness and sensitivity of MR cisternography as noninvasive study in the diagnosis of CSF fistula in patients with clinical diagnosis CSF rhinorrhea or otorrhea.

Method: Thirty-five patients with clinically diagnosed CSF leakage were examined for site of dural tear with MR cisternography with additional plain high-resolution CT in some cases from Jan. 1999 to Dec.