A randomized controlled trial investigating the effect of liraglutide on self-reported liking and neural responses to food stimuli in participants with obesity.

Background/objectives: Obesity is a complex condition and the mechanisms involved in weight gain and loss are not fully understood. Liraglutide, a GLP-1 receptor agonist, has been demonstrated to successfully promote weight loss in patients with obesity (OB). Yet, it is unclear whether the observed weight loss is driven by an alteration of food liking.

[Eating disorder and food addiction in a population candidates for a bariatric surgery].

Non stabilized severe eating disorder is a contra-indication for bariatric surgery. Specific cares can stabilize this disorder, and therefore a surgery can be undertaken. In this respect, more and more attention is paid to the concept of food addiction even if its definition is still debated.

[Not all patients might benefit from gastric by-pass].

Obesity is a chronic disease with a need for long-term follow-up. Bariatric surgery is very beneficial for patients who are not able to lose weight by lifestyle modifications alone. However, some patients present a weight regain after surgery.

[How to support obese patients in a long-term process of change?].

It is illusory to think losing weight effectively by acting only on diet or physical activity. To lose weight satisfactorily and to maintain that weight loss, we should move more on lifestyle changes, namely changes in behavior on several axes. Through concrete examples of an obese patient wanting to lose weight, we will see what skills he must acquire to achieve its objective and what tools the therapist can use to help.