Publications by authors named "Loic Couderc"
Article Synopsis
- The Chlamydiales order consists of intracellular pathogens that can infect a variety of hosts, including mammals and amoebas.
- The study reveals that while most Chlamydiales families retain a key glycogen metabolism pathway (the GlgC-pathway), the Criblamydiaceae and Waddliaceae families have a defective version and instead utilize a trehalose-dependent pathway (GlgE-pathway).
- Overall, the research emphasizes the importance of glycogen metabolism for the survival and virulence of these bacteria, challenging previous assumptions about storage polysaccharides in this group.
Motivation: Advances in the sequencing of uncultured environmental samples, dubbed metagenomics, raise a growing need for accurate taxonomic assignment. Accurate identification of organisms present within a community is essential to understanding even the most elementary ecosystems. However, current high-throughput sequencing technologies generate short reads which partially cover full-length marker genes and this poses difficult bioinformatic challenges for taxonomy identification at high resolution.
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