Normalization of Deviation: Quotation Error in Human Factors.

Objective The objective of this paper is to examine quotation error in human factors. Background Science progresses through building on the work of previous research. This requires accurate quotation.

[Perioperative handling of anticoagulation].

A growing number of patients in Germany receive a long-term prophylactic anticoagulation with phenprocoumone or one of the novel direct oral anticoagulants (NOAC), such as dabigatran, rivaroxaban or apixaban. The most common indication for an oral anticoagulant therapy is atrial fibrillation (approximately 75%) where the anticoagulant therapy can reduce the risk for an embolic event, particularly stroke by 60%. Operations carried out during such a therapy can result in major bleeding complications.

Are parental self-efficacy and family flexibility mediators of treatment for anorexia nervosa?

Objective: Family-based treatment (FBT) for adolescent anorexia nervosa (AN) promotes faster weight restoration when compared to other treatments. However, the mechanisms through which this occurs are not clarified. This study explored the trajectories of parental self-efficacy and perceived family flexibility during FBT and systemic family therapy (SyFT).

[Perioperative handling of immunosuppressive therapy].

Every year 16 million operations are performed in Germany. Many patients have an autoimmune disorder, for example rheumatoid arthritis, psoriasis or chronic inflammatory bowel disease, which requires treatment. Immunosuppressants are widely applied.

[The use of tumor therapeutics in the perioperative period].

In 2010 Germany had 447,300 new cases of cancer. From 2000 to 2010 the incidence of cancer increased by 21% in men and by 14% in women. The change in the age structure with an aging population is the crucial influencing factor.

[Perioperative handling of antidiabetic drugs].

Diabetes mellitus is the most frequent metabolic disorder in the western world with a prevalence of 3% in adults under 65 years of age and 14.3% in adults over 65 years of age. Due to the increasing age of our population, the number of patients taking oral antidiabetic drugs has increased.

[The use of platelet aggregation inhibitors in the perioperative period].

Every year 16 million operations are performed in Germany. Many patients take platelet aggregation inhibitors as a primary or secondary prevention to reduce the risk of cardiovascular events. Especially during the perioperative period, this risk reduction is relevant due to an increased risk for cardiac events (in approximately 6.

Emulation of Colonic Oxygen Gradients in a Microdevice.

Gut-on-a-chip in vitro modeling is an emerging field, as the human gut epithelium and gut microbiome have been recently identified as novel drug targets for a wide variety of diseases. Realistic in vitro gut models require a variety of precise environmental cues, such as chemical and gas gradients, in combination with substrates like mucus that support the growth of microbial communities. This technical brief describes a microfluidic architecture capable of developing a physiologically relevant oxygen gradient that emulates the oxygen profile proximal to the epithelial inner lining of the human colon.

Feasibility Study Combining Art Therapy or Cognitive Remediation Therapy with Family-based Treatment for Adolescent Anorexia Nervosa.

Adolescents with anorexia nervosa who have obsessive-compulsive (OC) features respond poorly to family-based treatment (FBT). This study evaluated the feasibility of combining FBT with either cognitive remediation therapy (CRT) or art therapy (AT) to improve treatment response in this at-risk group. Thirty adolescents with anorexia nervosa and OC features were randomized to 15 sessions of FBT + CRT or AT.

Mucus models to evaluate the diffusion of drugs and particles.

Mucus is a complex hydrogel that acts as a natural barrier to drug delivery at different mucosal surfaces including the respiratory, gastrointestinal, and vaginal tracts. To elucidate the role mucus plays in drug delivery, different in vitro, in vivo, and ex vivo mucus models and techniques have been utilized. Drug and drug carrier diffusion can be studied using various techniques in either isolated mucus gels or mucus present on cell cultures and tissues.

Rainbows by elliptically deformed drops. II. The appearance of supernumeraries of high-order rainbows in rain showers.

The appearance of supernumeraries of high-order rainbows in heavy rain showers is explored for rainbows up to order five (p=6). This is done by using a combination of the ray-theory-based first-order Möbius approximation for high-order rainbows with the Airy approximation of the rainbow radiance distribution. We conclude that supernumerary formation of rainbows of order three, four, and five is possible in natural rain showers.

Rainbows by elliptically deformed drops. I. Möbius shift for high-order rainbows.

Using ray theory, the Möbius shift of the (p-1)-order rainbow angle for a particle having an elliptical cross section is obtained to first order in the ellipticity as a function of the tilt of the ellipse with respect to the propagation direction of the incoming rays. The result is then adapted to the geometry of scattering of light rays from the sun by a falling water drop as a function of sun height angle. The variation in the angular spacing between the supernumeraries is determined as a function of location along the rainbow arc, the conditions under which the rainbow angle is insensitive to drop flattening were determined, and the dependence of the Möbius shift on the drop refractive index is shown for rainbows up to fourth order (p=5).

High-order rainbows of a spherical particle produced by near-grazing incident light.

This study is concerned with the formation of high-order rainbows by near-grazing light incident on a spherical particle. As the number of internal reflections involved increases, the incident Descartes ray strikes the sphere surface increasingly closer to its edge, where the predictions of ray theory and Airy theory become invalid. The deflection angle of the confluence of the stationary points of the phase of the partial wave scattering amplitudes is studied as a function of rainbow order and sphere radius.

Transmission bows of radially inhomogeneous spheres.

We consider transmission scattering of a plane wave by a radially inhomogeneous sphere containing a localized region of refractive index decrease. In ray theory, the boundary conditions on the deflection angle at axial and grazing incidence determine that transmission scattering gives rise to an even number of bows, half of them being relative maximum bows and half being relative minimum bows. For a model refractive index profile, we determine the conditions under which different numbers of bows occur, and we suggest physical mechanisms responsible for producing them.

Attention networks in adolescent anorexia nervosa.

Anorexia nervosa (AN) usually develops during adolescence when considerable structural and functional brain changes are taking place. Neurocognitive inefficiencies have been consistently found in adults with enduring AN and were suggested to play a role in maintaining the disorder. However, such findings are inconsistent in children and adolescents with AN.

Parental perceptions of childhood seasonal influenza vaccination in Singapore: A cross-sectional survey.

Purpose: Seasonal influenza vaccination is recommended in children aged 6-59months, but little is known about child vaccination coverage and determinants in Asian settings. We report the results of a survey of knowledge, attitudes, practices, and determinants of child influenza vaccination in Singapore.

Methods: In December 2015-March 2016, we conducted a survey of 332 parents of children aged 6months to 5years attending pre-schools.

Themes arising in clinical consultation for therapists implementing family-based treatment for adolescents with anorexia nervosa: a qualitative study.

Background: Our study aims to explore and describe themes arising in sessions of clinical consultation with therapists implementing Family-Based Treatment (FBT) for adolescents with Anorexia Nervosa (AN). There is currently no literature describing the content of clinical consultation for FBT. Thus, this knowledge will add to the evidence-base on what therapists need from consultants in ongoing clinical consultation.

Pupillary responses to light are not affected by narrow irido-corneal angles.

Chromatic pupillometry is an emerging method for evaluating ocular health that relies upon the differential stimulation of rods, cones, and intrinsically photosensitive retinal ganglion cells (ipRGCs). Although it has been investigated in conditions affecting the outer or inner retina, there is a paucity of studies in conditions where the anterior chamber of the eye is affected. Primary angle closure suspects (PACS) are defined as eyes with narrow anterior chamber angles and intact retina.

[Management of traumatic intestinal injury of mass casualties].

While intestinal injury is relatively rare in blunt abdominal trauma, it is common in penetrating abdominal trauma. Intestinal injury cannot be detected effectively by computed tomography (CT); therefore penetrating abdominal injury or abdominal signs in blunt trauma require liberal indications for explorative laparotomy. In mass casualty situations patients with hemodynamic instability and abdominal signs should be prioritized for surgery.