Publications by authors named "Lobna K Hamed"
Article Synopsis
- - Neural progenitor cells extend their cell cycle to prepare for differentiation during development, but it's unclear how they manage this lengthening without getting stuck.
- - Researchers found that N-methyladenosine (mA) methylation of certain mRNAs helps ensure the timely progression of late-born retinal progenitor cells (RPCs), which have longer cell cycles.
- - The deletion of a key enzyme (Mettl14) essential for mA methylation caused delayed exit from the cell cycle in late-born RPCs, while mA sequencing uncovered that mA-targeted mRNAs linked to cell cycle elongation were degraded, facilitating proper cell cycle management.
