Objective: To evaluate the response to second vaccination series among post-booster sero-negative children who had previously received compulsory HBV vaccination.
Subjects And Methods: After given a booster dose to 1070 children, 103 of them failed to generate anamnestic response (anti-HBs <10 IU/L). Only 91/103 children received additional two doses of recombinant HBV vaccine (i.