Anti-hypertensive effects of extract on Reno-vascular hypertensive rats.

Objectives: This study aims to investigate the anti-hypertensive effects of aqueous extract of and their underlying mechanism using a two-kidney one-clip (2K1C) model of reno-vascular hypertension in rats.

Methods: The reno-vascular hypertensive rats were treated with leaf extract (100 and 500 mg/kg; p.o.

Mapping-by-Sequencing via MutMap Identifies a Mutation in Underlying Fasciation in a Newly Developed EMS Mutant Population in an Elite Tropical Maize Inbred.

Induced point mutations are important genetic resources for their ability to create hypo- and hypermorphic alleles that are useful for understanding gene functions and breeding. However, such mutant populations have only been developed for a few temperate maize varieties, mainly B73 and W22, yet no tropical maize inbred lines have been mutagenized and made available to the public to date. We developed a novel Ethyl Methanesulfonate (EMS) induced mutation resource in maize comprising 2050 independent M2 mutant families in the elite tropical maize inbred ML10.