Publications by authors named "Loalo'a El Sherif"
Background: While the prevalence of rheumatic heart disease (RHD) in Egypt is relatively high, data on the awareness of Egyptians about the cause of RHD are lacking.
Methods: Using a pre-tested questionnaire, we performed a multicenter survey of outpatients attending 15 university hospitals across Egypt.
Results: A total of 6958 participants were interviewed.
Safety and Efficacy of Teplizumab for Treatment of Type One Diabetes Mellitus: A Systematic Review and Meta-Analysis.
Endocr Metab Immune Disord Drug Targets
March 2022
Article Synopsis
- Teplizumab, a humanized anti-CD3 monoclonal antibody, may help reduce insulin dependency in type 1 diabetes mellitus (T1DM) patients, as shown in eight randomized clinical trials with 866 participants.
- The study found that patients taking teplizumab needed less insulin at multiple 6, 12, 18, and 24-month intervals, and displayed increased levels of C-peptide, indicating beta cell function.
- However, teplizumab did not significantly affect HbA1c levels and was associated with some adverse effects, including lymphopenia and skin disorders.
Background: Two tocolytic drugs-atosiban and nifedipine-are currently used for first-line treatment of preterm labor (PTL).
Objective: To compare the efficacy and safety of atosiban with nifedipine for PTL treatment.
Search Strategy: In May 2017, we searched PubMed, Scopus, Web of Science, and Cochrane Central Register of Controlled Clinical Trials with search terms including "nifedipine", "atosiban", and "preterm labor".