Parental Demandingness Predicts Adolescents' Rumination and Depressive Symptoms in a One-year Longitudinal Study.

While past research has linked parental demandingness (parents' rules, regulations, and restrictions for their children) to depression in adolescents, the mechanism underlying this relationship has not been well understood. This study attempts to disentangle the association between parental demandingness and depression by examining the potential mediating role of rumination (a repetitive and passive focus on negative emotions and symptoms) using an objective observational measure of parenting and a two-wave longitudinal design. Participants were 125 students aged 9 to 14 (M = 12.

Help-Seeking Behaviors of Transition-Aged Youth for Mental Health Concerns: Qualitative Study.

Background: Transition-aged youth are particularly vulnerable to mental health problems, yet they are one of the least likely demographic groups to seek help.

Objective: The aim of this study is to explore the influences on and patterns in help-seeking for mental health concerns among transition-aged youth who attend postsecondary schools in Canada.

Methods: A qualitative research design was used, involving 12 semistructured focus groups with transition-aged youth (17-29 years) who attended postsecondary schools in Canada.

DBAN: Adversarial Network With Multi-Scale Features for Cardiac MRI Segmentation.

With the development of medical artificial intelligence, automatic magnetic resonance image (MRI) segmentation method is quite desirable. Inspired by the power of deep neural networks, a novel deep adversarial network, dilated block adversarial network (DBAN), is proposed to perform left ventricle, right ventricle, and myocardium segmentation in short-axis cardiac MRI. DBAN contains a segmentor along with a discriminator.

Systematic review of the prevalence and development of osteoporosis or low bone mineral density and its risk factors in patients with inflammatory bowel disease.

Background: The inflammatory bowel diseases (IBD), Crohn's disease (CD) and ulcerative colitis (UC) are chronic, immune-mediated disorders of the digestive tract. IBD is considered to be a risk factor for developing osteoporosis; however current literature on this matter is inconsistent.

Aim: To assess prevalence and development of osteoporosis and low bone mineral density (BMD), and its risk factors, in IBD patients.

Prevalence of therapeutic failure and evolution of biological factors amongst people living with HIV enrolled in antiretroviral therapy at the Ambulatory Treatment Center in Nouakchott, Mauritania.

Goal: The goal of this study is to determine the prevalence of therapeutic failure and the evolution of the biological factors after 6 and 12 months of anti-retroviral treatment (ART) amongst human immunodefeciency virus (HIV) Patients receiving care through the Ambulatory Treatment Center in Nouakchott.

Methods: The study presents a descriptive and retrospective analysis of 479 patients enrolled in ART between January 2015 and January 2019, with focus on treatment failures and related biomarkers. The average age of the patients studied was 37 ± 12.

Balancing the Blood Component Transfusion Ratio for High- and Ultra High-Dose Cell Salvage Cases.

Objective: To assess the ratio of non-red blood cell to red blood cell components required to avoid coagulopathy when transfusing large amounts of salvaged blood using laboratory test-guided therapy.

Design: Retrospective cohort study.

Setting: Single-center, academic hospital.

Counting Bites and Recognizing Consumed Food from Videos for Passive Dietary Monitoring.

Assessing dietary intake in epidemiological studies are predominantly based on self-reports, which are subjective, inefficient, and also prone to error. Technological approaches are therefore emerging to provide objective dietary assessments. Using only egocentric dietary intake videos, this work aims to provide accurate estimation on individual dietary intake through recognizing consumed food items and counting the number of bites taken.

Blood utilization and clinical outcomes in pancreatic surgery before and after implementation of patient blood management.

Background: Over the past decade, patient blood management (PBM) programs have been developed to reduce allogeneic blood utilization. This is particularly important in pancreatic surgery, which has historically been associated with high transfusion requirements and morbid event rates. This study investigated blood utilization and clinical outcomes in pancreatic surgery before, during, and after the implementation of PBM.

Local excision for T1 rectal tumours: are we getting better?

Aim: The objective was to assess the effect of three different surgical treatments for T1 rectal tumours, radical resection (RR), open local excision (open LE) and laparoscopic local excision (laparoscopic LE), on overall survival (OS).

Methods: Adults from the National Cancer Database (2008-2016) with a diagnosis of T1 rectal cancer were stratified by treatment type (LE vs RR). We assumed that laparoscopic LE equates to transanal minimally invasive surgery (TAMIS) or transanal endoscopic microsurgery.

Validation of ulcerative colitis and Crohn's disease and their phenotypes in the Danish National Patient Registry using a population-based cohort.

Introduction: The Danish National Patient Registry (DNPR) has been the source of several epidemiological studies of inflammatory bowel disease (IBD). However, the validation dates back to 1996 and lacks outpatient records and disease classification. The aim of this study was to update the validation and assess the validity and reliability of using the registry in disease classification.

Do specific operative approaches and insurance status impact timely access to colorectal cancer care?

Introduction: The increased use of minimally invasive surgery in the management of colorectal cancer has led to a renewed focus on how certain factors, such as insurance status, impact the equitable distribution of both laparoscopic and robotic surgery. Our goal was to analyze surgical wait times between robotic, laparoscopic, and open approaches, and to determine whether insurance status impacts timely access to treatment.

Methods: After IRB approval, adult patients from the National Cancer Database with a diagnosis of colorectal cancer were identified (2010-2016).

The Risk of Extraintestinal Cancer in Inflammatory Bowel Disease: A Systematic Review and Meta-analysis of Population-based Cohort Studies.

Background & Aims: Patients with Crohn's disease (CD) and ulcerative colitis (UC) are at increased risk of developing intestinal cancer. However, less is known about the risk of extraintestinal cancers (EICs). The aim of this study was to conduct a systematic review and meta-analysis of population-based cohorts assessing the risk of EICs in inflammatory bowel disease (IBD) patients.

Cross-Subject and Cross-Modal Transfer for Generalized Abnormal Gait Pattern Recognition.

For abnormal gait recognition, pattern-specific features indicating abnormalities are interleaved with the subject-specific differences representing biometric traits. Deep representations are, therefore, prone to overfitting, and the models derived cannot generalize well to new subjects. Furthermore, there is limited availability of abnormal gait data obtained from precise Motion Capture (Mocap) systems because of regulatory issues and slow adaptation of new technologies in health care.

Changes to the ACGME Common Program Requirements and Their Potential Impact on Emergency Medicine Core Faculty Protected Time.

The Accreditation Council for Graduate Medical Education (ACGME), which regulates residency and fellowship training in the United States, recently revised the minimum standards for all training programs. These standards are codified and published as the Common Program Requirements. Recent specific revisions, particularly removing the requirement ensuring protected time for core faculty, are poised to have a substantial impact on emergency medicine training programs.

Multistrain Probiotic Increases the Gut Microbiota Diversity in Obese Pregnant Women: Results from a Randomized, Double-Blind Placebo-Controlled Study.

Background: Maternal obesity is associated with adverse pregnancy outcomes. Probiotic supplementation during pregnancy may have positive effects on blood glucose, gestational weight gain (GWG), and the risk of gestational diabetes mellitus [GDM and glycated hemoglobin (HbA1c)].

Objectives: This feasibility study involved a daily probiotic intervention in obese pregnant women from the early second trimester until delivery.

Cellular markers of mule duck livers after force-feeding.

The "Foie gras" or fatty liver is the result of hepatic steatosis from nutritional origin and induced by the force-feeding of palmipeds. Despite identical rearing and force-feeding conditions of ducks from the same breed, different liver weights, within a range of 500 to more than 700 g, are generally observed at the time of evisceration. To better understand the determinism of this large variability in fatty liver weights, the activity of various metabolic pathways has been explored in 4 groups of steatotic livers differing by their weights.

Chemical state tuning of surface Ce species on pristine CeO with 2400% boosting in peroxidase-like activity for glucose detection.

We demonstrate that the Ce reactivity of CeO towards HO is dictated by its local structure and electron density. More than 2400% increase in peroxidase-like activity has been achieved on the (100) surface for glucose detection due to the promoted HO adsorption and subsequent activation by the electron-rich Ce species.

Identifying best approaches for engaging patients and family members in health informatics initiatives: a case study of the Group Priority Sort technique.

Background: Patient engagement strategies in health service delivery have become more common in recent years. However, many healthcare organizations are challenged in identifying the best methods to engage patients in health information technology (IT) initiatives. Engaging with important stakeholders to identify effective opportunities can inform the development of a resource that addresses this issue and supports organizations in their endeavors.

Identifying Novel Mutations in Iranian Patients with LPS-responsive Beige-like Anchor Protein (LRBA) Deficiency.

LPS-responsive beige-like anchor protein (LRBA) deficiency is a monogenic primary immunodeficiency characterized by a heterogeneous spectrum of clinical manifestations associated with immune dysregulation. In this study, we reported clinical, immunologic, and genetic evaluation of two Iranian patients from unrelated families, both suffering from recurrent respiratory tract infections, failure to thrive, interstitial lung disease, autoimmune cytopenia, and hypogammaglobulinemia. Pulmonary abscess in one patient and persistent enteropathy in another were also observed.

Ripple Effects of a Community-Based Randomized Trial for Rural Women: Strong Hearts, Healthy Communities.

Objective: This study aimed to examine (1) whether the Strong Hearts, Healthy Communities intervention (SHHC) improved social network members' (SNMs') weight, exercise, and diet and (2) whether SNMs' weight and behavioral changes were modified by their relationship closeness and/or spatial closeness with trial participants.

Methods: Eight towns received the SHHC intervention, which focused on building individual healthy behaviors and creating supportive social and built environments for exercise and healthy eating. Eight towns received an education-only control intervention.

Clinical, Immunological, and Genetic Features in 49 Patients With ZAP-70 Deficiency: A Systematic Review.

Zeta-Chain Associated Protein Kinase 70 kDa (ZAP-70) deficiency is a rare combined immunodeficiency (CID) caused by recessive homozygous/compound heterozygous loss-of-function mutations in the gene. Patients with ZAP-70 deficiency present with a variety of clinical manifestations, particularly recurrent respiratory infections and cutaneous involvements. Therefore, a systematic review of ZAP-70 deficiency is helpful to achieve a comprehensive view of this disease.

Clinical, Immunological, and Genetic Features in Patients with Immune Dysregulation, Polyendocrinopathy, Enteropathy, X-linked (IPEX) and IPEX-like Syndrome.

Background: Immune dysregulation, polyendocrinopathy, enteropathy, X-linked (IPEX) syndrome is a rare inborn error of immunity caused by mutations in the forkhead box P3 (FOXP3) gene.

Objective: In this study, we conducted a systematic review of patients with IPEX and IPEX-like syndrome to delineate differences in these 2 major groups.

Methods: The literature search was performed in PubMed, Web of Science, and Scopus databases, and demographic, clinical, immunologic, and molecular data were compared between the IPEX and IPEX-like groups.