Publications by authors named "Lloyd Zucker"
Objective: Greater extent of resection (EOR) is associated with longer overall survival in patients with high-grade gliomas (HGGs). 5-Aminolevulinic acid (5-ALA) can increase EOR by improving intraoperative visualization of contrast-enhancing tumor during fluorescence-guided surgery (FGS). When administered orally, 5-ALA is converted by glioma cells into protoporphyrin IX (PPIX), which fluoresces under blue 400-nm light.
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- A novel minimally invasive method for clot evacuation in intracranial hemorrhage was tested across multiple centers, showing promising safety and effectiveness.
- The integrated approach consists of key techniques like image planning, dynamic navigation, and atraumatic access to improve surgical outcomes.
- Results from 39 patients displayed significant improvement in GCS scores post-surgery, with over 70% achieving high rates of hematoma evacuation and no reported fatalities.
Article Synopsis
- The study looks at how traumatic brain injuries (TBI) affect older people, focusing on whether monitoring brain pressure makes a difference in their recovery.
- Researchers analyzed data from a large trauma database for patients over 55 who needed brain pressure monitoring but found that only 11.2% actually received it.
- The results showed that older patients who had their brain pressure monitored had higher death rates and were less likely to leave the hospital in good shape compared to those who didn’t have monitoring.
Object: The direct thrombin inhibitor dabigatran has recently been approved in the US as an alternative to warfarin. The lack of guidelines, protocols, and an established specific antidote to reverse the anticoagulation effect of dabigatran potentially increases the rates of morbidity and mortality in patients with closed head injury (CHI). Confronted with this new problem, the authors reviewed their initial clinical experience.
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