Publications by authors named "Ljubica Lindholm"

The significance of specific lipids for proton pumping by the bacterial rhodopsin proteorhodopsin (pR) was studied. To this end, it was examined whether pR preferentially binds certain lipids and whether molecular properties of the lipid environment affect the photocycle. pR's photocycle was followed by microsecond flash-photolysis in the visible spectral range.

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The membrane protein monoglucosyldiacylglycerol synthase (MGS) from Acholeplasma laidlawii is responsible for the creation of intracellular membranes when overexpressed in Escherichia coli (E. coli). The present study investigates time dependent changes in composition and properties of E.

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Article Synopsis
  • SMA-Lipodisq nanoparticles were created with an average of one bacteriorhodopsin protein per 12 nm, using a protein/lipid ratio of 1:172 and without detergents.
  • Electron paramagnetic resonance techniques showed that the structure and dynamics of bacteriorhodopsin were preserved in these nanoparticles compared to its native and detergent-based environments.
  • This suggests that Lipodisq nanoparticles could serve as effective models for studying membrane proteins in a simulated environment.
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