The Crucial Triad: Endothelial Glycocalyx, Oxidative Stress, and Inflammation in Cardiac Surgery-Exploring the Molecular Connections.

Since its introduction, the number of heart surgeries has risen continuously. It is a high-risk procedure, usually involving cardiopulmonary bypass, which is associated with an inflammatory reaction that can lead to perioperative and postoperative organ dysfunction. The extent of complications following cardiac surgery has been the focus of interest for several years because of their impact on patient outcomes.

Mitral regurgitation and coronary artery bypass surgery: comparison of mitral valve repair and replacement.

Background: The aim of this retrospective study was to determine if there is a statistically significant difference (p < or = 0.05) between mitral valve repair (MVRp) with concomitant surgical revascularization of the myocardium (CABG) and mitral valve replacement (MVR) with concomitant CABG, considering the duration of surgery, early postoperative morbidity, in-hospital mortality, length of stay in the Intensive Care Unit (ICU) and overall in-hospital stay.

Methods: Between January 1st 2006 and December 31st 2008, 75 patients underwent surgery for mitral regurgitation and ischemic heart disease.