The importance of Myd88 L265P mutation, clinical and immunohistochemical prognostic factors for the survival of patients with diffuse large B-cell non-Hodgkin lymphoma treated by immunochemotherapy in southeast Serbia.

Purpose: Immunochemotherapy used in the treatment of non-Hodgkin diffuse large B-cell lymphoma (DLBCL) modifies the course of disease and has a positive effect on overall survival (OS). The purpose of this study was to verify the existence of the important Myd 88 mutation and other immunohistochemical factors on disease prognosis in patients with DLBCL in southeast Serbia.

Methods: Immunohistochemical expression of CD10, Bcl- 2, Bcl-6, Ki-67 and MUM 1 was performed using paraffin blocks of DLBCL.

Household environmental tobacco smoke and respiratory diseases among children in Nis (Serbia).

The authors investigated the relationship between household environmental tobacco smoke (ETS) exposure and prevalence of respiratory symptoms and diseases as well as absenteeism related to respiratory illness in schoolchildren. The study sample consisted of 1,074 children aged 7-11 years from three primary schools in Nis (Serbia). ETS exposure was associated with wheezing (OR-1.

Radiation therapy with or without concurrent low-dose daily chemotherapy in locally advanced, nonmetastatic squamous cell carcinoma of the head and neck.

Purpose: To retrospectively investigate the difference between conventionally fractionated (CF) and hyperfractionated (Hfx) radiation therapy (RT), with and without either daily cisplatin (CDDP) or carboplatin (CBDCA), in patients with locally advanced squamous cell carcinoma of the head and neck (SCCHN) enrolled onto two consecutive prospective randomized studies.

Patients And Methods: Treatment consisted of CF RT (70 Gy, group 1), CF RT and either daily CDDP (6 mg/m2) or daily CBDCA (25 mg/m2; group 2), Hfx RT (77 Gy, 1.1 Gy bid; group 3), or Hfx RT and daily CDDP (group 4).

[Cytology in the diagnosis of diseases of the nose and maxilary sinuses].

The aim of this work is to evaluate cytologic examination of secretions of nose and maxillary sinuses in patients with naso-sinusal disorders. The material for cytologic examination is taken from 128 nasal cavities of 101 patients with inflammation or tumour diseases of nose and maxillary sinuses, and from 114 maxillary sinuses, intraoperatively, of 89 patients. The results of cytological examinations were classified in five groups: acute bacterial inflammations, chronic bacterial inflammations, allergic processes, viral infections and positive findings for malignancy.

[Relation between size of the nasopharynx and occurrence of chronic otitis media].

Aetiopathogenesis of chronic middle ear inflammation has not yet been sufficiently elucidated. Eustachian tube infection, causative organism virulence, immune status and biologically predisposed middle ear mucosa play the major role. The study was aimed at evaluation of the correlation between nasopharyngeal size and development of chronic middle ear inflammations.