Publications by authors named "Lizzie Meadows"
Article Synopsis
- The analysis involved whole genome sequencing of 1565 positive samples collected from various healthcare settings, revealing 26 global lineages and 100 locally evolving UK lineages.
- Key findings included a specific sublineage linked to care facilities, no instances of reinfection, and the ability to rule out hospital-related outbreaks, contributing valuable data to national and local pandemic responses.
We present CoronaHiT, a platform and throughput flexible method for sequencing SARS-CoV-2 genomes (≤ 96 on MinION or > 96 on Illumina NextSeq) depending on changing requirements experienced during the pandemic. CoronaHiT uses transposase-based library preparation of ARTIC PCR products. Method performance was demonstrated by sequencing 2 plates containing 95 and 59 SARS-CoV-2 genomes on nanopore and Illumina platforms and comparing to the ARTIC LoCost nanopore method.
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