Publications by authors named "Lizhong Yao"

Article Synopsis
  • - This study focuses on improving predictions from mild cognitive impairment (MCI) to Alzheimer's disease (AD) using advanced deep learning techniques that account for changes in brain structure over time, rather than just relying on single-time point data.
  • - It introduces a lightweight 3D convolutional neural network that employs a unique feature selection strategy to identify important brain features from longitudinal imaging data, enhancing the model's ability to detect subtle structural differences.
  • - The model also includes a mechanism to focus on disease trends and improve prediction visualization, showing significant improvements in predictive performance—achieving an area under the curve (AUC) of 79.03% with only two brain scans taken 24 months apart.
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Collaboratively optimizing operational parameters through leveraging accumulated production experience is an innovative approach to reducing energy consumption in aluminum electrolysis cells (AECs). Due to the dynamic heterogeneity of various AECs, an explicit evolutionary multitasking (EMT) framework capable of incorporating different optimizers, has the potential to tackle this challenge effectively. However, there is a notable gap in theoretical research on multitasking collaborative evolutionary algorithms specifically applied to AECs.

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Objective: To explore the effect of dietary modification-assisted multimodal therapy in the prevention and treatment of chronic prostatitis.

Methods: A total of 132 cases of chronic prostatitis treated in the Outpatient Department of our hospital were randomly divided into an observation group (n = 68) and a control group (n = 64), the former following the Mediterranean dietary pattern, the latter adhering to their own dietary habits, and meanwhile both receiving lifestyle guidance, psychological counseling, symptomatic medication and physiotherapy according to their specific symptoms. The patients were followed up for 4 weeks, therapeutic effects were observed and comparisons were made between the two groups in the NIH-CPSI scores before and after treatment.

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Purpose: Elevated blood lipids are considered a risk factor for atherosclerosis, which can lead to erectile dysfunction. This study aimed to explore the relationship between the atherogenic index of plasma (AIP), atherogenic coefficient (AC), Castelli's risk index-I (CRI-I), Castelli's risk index-II (CRI-II), and erectile dysfunction.

Methods: Based on the National Health and Nutrition Examination Survey (NHANES) data from 2001-2004, multivariable-adjusted logistic regression models were used to evaluate the association between AIP, AC, CRI-I, and CRI-II with ED.

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As the predominant immunosuppressive component within the tumor microenvironment (TME), cancer-associated fibroblasts (CAFs) inhibit Natural Killer cell (NK cell) activity to promote tumor progression and immune escape; however, the mechanisms of cross-talk between CAFs and NK cells in gastric cancer (GC) remain poorly understood. In this study, we demonstrate that NK cell levels are inversely correlated with CAFs abundance in human GC. CAFs impair the anti-tumor capacity of NK cells by inducing ferroptosis, a cell death process characterized by the accumulation of iron-dependent lipid peroxides.

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The mechanical microenvironment regulated by cancer-associated fibroblasts (CAFs) influence tumor progression. Chemotherapeutic interventions including 5-Fluorouracil (5-Fu) are commonly used for primary treatment of patients with advanced gastric cancer (GC), and the development of acquired resistance to 5-Fu limits the clinical efficacy of these chemotherapies. However, if and how the interplay between CAFs and the mechanical microenvironment regulates GC response to 5-Fu is poorly understood.

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There are plenty of risk factors associated with splenic hilar lymph node metastasis (SHLNM) in patients with advanced gastric cancer (AGC). Whereas, their main influencing factors have not reached a consensus yet. The aim of the study is to investigate the related clinicopathological factors influencing SHLNM in AGC.

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With community character indices and principal component analysis, this paper studied the variation of insect community composition and structure in Chinese prickly ash plantations at four altitudes in Yunnan Province, and analyzed the temporal patterns of the variation and its affecting factors. The results showed that with the increase of altitude, the species diversity, abundance and evenness of the community decreased gradually, while the population number had a certain increase. Such a variation was more obvious with time.

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