Effects of short-term exposure to printing shop particles on inflammatory responses and DNA damage in healthy young adults.

Considering the increasingly demand for printing in daily life, more attention should be paid to the health risks of printer emissions to consumers. This study designed a two-stage cross-over study with 20 volunteers to investigate whether the short-term exposure to printing shop particles (PSPs) could cause inflammatory responses and genetic damage in healthy young volunteers. According to the study, short-term exposure to high level of PSPs caused the elevation of eotaxin and TNF-α levels in serum, indicating PSPs exposure led to the inflammation in healthy subjects.

Oral intake of titanium dioxide nanoparticles affect the course and prognosis of ulcerative colitis in mice: involvement of the ROS-TXNIP-NLRP3 inflammasome pathway.

Background: Titanium dioxide (TiO), no matter in nanoscale or micron sizes, has been widely used in food industry as additives for decades. Given the potential impact of TiO on the gastrointestinal epithelial and parenchymal cells, including goblet cells, the public consumers may suffer the risk of diseases caused by its widespread dissemination in food products. We therefore set out to investigate the impact of TiO NPs on the course and prognosis of ulcerative colitis by oral gavaging TiO NPs at the doses levels of 0, 30, 100, and 300 mg/kg during the induction (7 days, from day 1 to day 7) and recovery (10 days, from day 8 to day 17) phases of colitis in mice.

A case study on occupational exposure assessment and characterization of particles in a printing shop in China.

Printers can release numerous particles to contaminate indoor environments and pose health risks. Clarifying the exposure level and physicochemical properties of printer-emitted particles (PEPs) will help to evaluate the health risks of printer operator. In our study, the particles concentration in the printing shop was monitored in real time for a long time (12 h/day, total 6 days), and the PEPs were collected to characterize their physicochemical properties including shape, size and compositions.

Characterization of titanium dioxide nanoparticles in confectionary products and estimation of dietary exposure level among the Chinese population.

Titanium dioxide (TiO) is widely used in the food industry. Recently, European Commission has banned TiO as a food additive, raising public concern about its health risk, especially the nanoparticles (NPs) contained therein. This study aimed to reveal the existence of TiO NPs in food and further estimate the dietary exposure level among Chinese population by characterizing particle size distribution, determining Ti content and micro-distribution in food products, and calculating food consumption from the China Health and Nutrition Survey (CHNS).

Changes in heart rate variability of healthy subjects shortly exposed to printing shop particles and the effect of air purifier intervention.

Particulate matter (PM) released by printers may cause airway inflammation and cardiac electrophysiological changes. We conducted a two-stage crossover study to examine the association between short-term exposure to printing shop particles (PSPs) and the heart rate variability (HRV) among healthy volunteers, as well as to evaluate the effect of air purifier intervention. The on-site assessments of PSPs and individual HRV parameters of the volunteers were used to analyze the influence of size-fractionated PSPs and air purifier intervention on HRV at different lag times after PSPs exposure (0 min, 5 min, 15 min, and 30 min) by using the linear mixed-effects models.

The Influence of Long-Term Dietary Intake of Titanium Dioxide Particles on Elemental Homeostasis and Tissue Structure of Mouse Organs.

: Titanium dioxide (TiO₂), consisting of nanoparticles and sub-microparticles, were widely used as food additive and consumed by people every day, which has aroused a public safety concern. Some studies showed TiO₂ can be absorbed by intestine and then distributed to different tissues after oral intake, which is supposed to affect the content of various elements in the body whereas led to tissue damage. However, knowledge gaps still exist in the impact of TiO₂ on the disorder of elemental homeostasis.

Impact of titanium dioxide nanoparticles on intestinal community in 2,4,6-trinitrobenzenesulfonic acid (TNBS)-induced acute colitis mice and the intervention effect of vitamin E.

Titanium dioxide nanoparticles (TiO2-NPs) are widely applied as additives in foods due to their excellent whitening and brightening capability. Although the toxicity and antibacterial activity of TiO2-NPs have been extensively studied, their impact on the gut microbiota in vivo still remains unclear, especially in animals with gastrointestinal disorders. In the present study, healthy mice and TNBS-induced colitis mice were administered with TiO2-NPs (38.

Health effects of occupational exposure to printer emissions on workers in China: Cardiopulmonary function change.

Printers emitted nanoparticles (NPs), ozone (O) and volatile organic chemicals (VOCs) during operation that elicited adverse effects on indoor air quality of the printing room, which may affect the health of exposed workers. The aim of this work was to explore the health effects of occupational exposure to printer emissions on workers, especially cardiovascular and lung function. We sampled particles in the print shop for characterization, including particle size distribution and elemental composition, and measured PM number concentrations in print shops and other workplaces.