Innate immune response is the first line of defense for the host against virus invasion. One important response is the synthesis and secretion of type I interferon (IFN-I) in the virus-infected host cells. Here, we found that respiratory syncytial virus (RSV) infection induced high expression of TRIM25, which belongs to the tripartite motif-containing (TRIM) family of proteins.
View Article and Find Full Text PDFIt is a worthy concern for us to understand virus-host interactions which affect progression and prognosis of disease. We demonstrated that the non-structural protein 1 of respiratory syncytial virus (RSV NS1) may act as a novel mitophagy receptor to induce mitophagy by binding LC3B and mitochondrial protein TUFM, and finally dampen interferon (IFN) responses induced by RIG1 and RSV infection. TUFM is beneficial for RSV replication and .
View Article and Find Full Text PDFRetroreflectors that can accurately redirect the incident waves in free space back along their original channels provide unprecedented opportunities for light manipulation. However, to the best of our knowledge, they suffer from either the bulky size, narrow angular bandwidths, or time-consuming postprocessing, which essentially limits their further applications. Here, a scheme for designing ultrathin all-angle real-time retroreflectors based on hyperbolic plasmonic metasurfaces is proposed and experimentally demonstrated.
View Article and Find Full Text PDFInspired by the capability of structured illumination microscopy (SIM) in subwavelength imaging, many researchers devoted themselves to investigating this methodology. However, due to the free-propagating feature of the traditional structured illumination fields, the resolution can be only improved up to two-fold of the diffraction-limited microscopy. Besides, most of the previous studies, relying on incoherent illumination sources, are restricted to fluorescent samples.
View Article and Find Full Text PDFTerahertz imaging has recently attracted great attention owing to the abilities of high penetration and low ionizing damages. However, the low resolution and low contrast resulting from the diffraction limit and unwanted background illumination significantly hinder the extensive usage. In this Letter, we propose and numerically demonstrate a terahertz subwavelength imaging method capable of extracting only the edges and fine features of the targets.
View Article and Find Full Text PDFManipulation of spoof surface plasmons (SSPs) has recently intrigued enormous interest due to the capability of guiding waves with subwavelength footsteps. However, most of the previous studies, manifested for a single functionality, are not suitable for multifunctional integrated devices. Herein, a bifunctional Luneburg-fish-eye lens is proposed based on a 2D metal pillar array.
View Article and Find Full Text PDFIn this Letter, we propose and experimentally demonstrate a simple but efficient method to excite spoof surface plasmons (SSP) through periodic metallic cylinders at microwave frequencies. The rigorous multiple scattering theory indicates that most of the incident propagating waves can pass the cylinders and be converted into the desired harmonics. Furthermore, by tuning the incident angle, controlling the directions of the excited SSP at different frequencies is also realized.
View Article and Find Full Text PDFSpoof surface plasmon (SSP) meta-couplers that efficiently integrate other diversified functionalities into a single ultrathin device are highly desirable in the modern microwave and terahertz fields. However, the diversified functionalities, to the best of our knowledge, have not been applied to circular polarization meta-couplers because of the spin coupling between the orthogonal incident waves. In this paper, we propose and demonstrate a terahertz spin-decoupled bifunctional meta-coupler for SSP excitation and beam steering.
View Article and Find Full Text PDFReflective multichannel metasurfaces are flat reflectors that can control incident and reflected waves in a number of propagating directions simultaneously. However, they are always densely discretized with a high spatial resolution, which increases the manufacturing complexity. In this Letter, to the best of our knowledge, a new method that combines the array antenna theory with the metagratings theory is proposed.
View Article and Find Full Text PDFIn this paper, we propose and numerically demonstrate a new way to realize superfocusing of terahertz waves via the spoof surface plasmons (SSP). With the assist of a modified subwavelength metallic grating, a near-field rapid oscillation can be formed, originating from the Fabry-Perot resonances due to the reflection of SSP waves at terminations. We show that the field pattern of oscillation on textured metallic surface can be engineered by adjusting groove width and grating number.
View Article and Find Full Text PDFAn ultra-broadband subwavelength resolution probe that consists of a Teflon rod and six metallic strips is developed for the near-field imaging system. The slit between two metallic strips maintains quasi-TEM modes, avoiding the problem of low coupling efficiency caused by the cutoff effect. The numerical calculations visualize the process of energy compression into a 0.
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