Association between Polymorphisms in Inflammatory Response-Related Genes and the Susceptibility, Progression and Prognosis of the Diffuse Histological Subtype of Gastric Cancer.

The chronic inflammatory microenvironment and immune cell dysfunction have been described as critical components for gastric tumor initiation and progression. The diffuse subtype is related to poor clinical outcomes, pronounced inflammation, and the worst prognosis. We investigated the association of polymorphisms in inflammatory response-related genes (, , , , , , , , , , and ) with gastric cancer susceptibility, progression and prognosis in a Brazilian sample, focusing on the diffuse subtype.

Resilience in low-income African American women living and aging with HIV.

Women are living with HIV into middle and older age and are likely to face multiple comorbidities and stressors as they age. This study focused on understanding how women who experience multiple forms of oppression and ongoing adversity are still able to adapt and stand strong. Using a theoretical framework of resilience and a feminist research ideology, interviews of eight middle-aged and older African American women living with HIV were analyzed.

Reinventing Mpowerment for black men: long-term community implementation of an evidence-based program.

Although research on the dissemination of evidence-based programs to community providers has rapidly grown, research describing implementation of evidence-based efforts remains a central need. Insight on implementation may aid in developing approaches to assisting organizations to use a variety of evidence-based practices effectively and to improve the design of programs that can and will be used faithfully. This mixed-method case study provides a descriptive account of the implementation of an evidence-based program designed principally for white gay and bisexual young men, the Mpowerment Project, in the 4th and 5th years after its initial adoption by an organization serving black gay and bisexual men.

Prevalence of sexually abusive experiences in childhood and adolescence among a community sample of Latinas: a descriptive study.

This study examined the prevalence, severity, and circumstances of self-reported sexually coercive and abusive experiences in childhood and adolescence in a community sample of Latina women (N=204) ages 18 to 34 years. Results from structured phone interviews indicated that 35% of the women reported experiencing some form of sexual abuse, 31% of the reported perpetrators were family members, and 52% were boyfriends, friends, or acquaintances. Of those who reported an abusive experience, 44% had not disclosed the abuse to anyone; for those who did disclose, 74% reported feeling supported.