Publications by authors named "Lize Angelo"
Keratoconus is a multifaceted corneal ectatic disorder characterized by a range of genetic and environmental risk factors. While genetic predisposition significantly influences global disease prevalence rates as well as severity and progression rates, emerging evidence highlights the critical interplay between environmental factors and genetic susceptibility. This article provides a comprehensive overview of environmental risk factors implicated in the onset and progression of keratoconus.
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- The study highlights the economic burden of keratoconus on patients and society, focusing on lifetime costs and expenditures related to management and treatment.
- It involved a survey of 110 participants from Auckland, revealing low visual rehabilitation rates and significant direct and indirect costs estimated at NZD 30.9 million annually, with individuals facing an average lifetime out-of-pocket expense of NZD 79,254.
- The findings emphasize the need for better funding and support, as the financial implications of keratoconus can pose barriers to effective management for patients.
Objectives: Defining the patterns of practice and referral criteria of optometrists within New Zealand to investigate the diagnosis and management of keratoconus.
Methods: Optometrists recruited through the New Zealand Association of Optometrists, Cornea and Contact Lens Society of New Zealand, and private practices were invited to complete an anonymous survey.
Results: Responses were received from 168 optometrists (representing 20.
Significance: Keratometry and pachymetry are important for diagnosis and monitoring of keratoconus. Many corneal imaging units exist, but comparison to determine repeatability and agreement is paramount for adequate keratoconus management in primary and secondary care.
Purpose: This study aimed to evaluate the repeatability and agreement of a Placido disc-based videokeratoscope (Melbourne, Victoria, Australia) used in primary care with spectral-domain optical coherence tomography (Optopol Technology, Zawiercie, Poland) and Scheimpflug corneal tomography (Oculus, Wetzlar, Germany) in secondary care.
Purpose: The aim of this study was to determine the barriers to accessing the crosslinking service in Auckland, New Zealand.
Methods: This was a prospective 1-year study of patients at Auckland District Health Board. Studied parameters included age, sex, body mass index, ethnicity, New Zealand Deprivation (NZDep; an area-based measure of socioeconomic status, 1 = low deprivation-10 = high deprivation) score of residence, disease severity (maximum keratometry and thinnest corneal thickness), attendance, distance travelled, car ownership, employment status, and visual outcomes.
Objective: To determine the repeatability limits of corneal tomography parameters in patients with advanced and moderately thin keratoconic corneas to assist in planning thickness-based procedural interventions.
Methods: Prospective, single-centre, repeatability study. Three tomography scans using the Pentacam AXL were obtained from patients with keratoconus with thinnest corneal thickness (TCT) ≦400 µm (sub-400 group) and compared to those with TCT = 450-500 µm (450-plus group).
Corneal cross-linking is a photopolymerization technique traditionally used to strengthen corneal tissue. Corneal cross-linking utilizes riboflavin (vitamin B2) as a photosensitizer and ultraviolet-A light (UVA) to create strong covalent bonds within the corneal stroma, increasing tissue stiffness. Multiple studies have demonstrated corneal cross-linking's effectiveness in treating corneal ectasia, a progressive, degenerative, and non-inflammatory thinning disorder, as quantified by key tomographic, refractive, and visual parameters.
View Article and Find Full Text PDFKeratoconus is a progressive corneal thinning disorder that can lead to vision loss. In the last 2 decades, corneal crosslinking (CXL) has emerged as an effective method to halt the progression of keratoconus and reduce the number of patients requiring keratoplasty. The procedure has been adopted globally and has evolved to become a part of combination treatments to regularize the cornea and improve visual outcomes.
View Article and Find Full Text PDFAim: This study was conducted to describe the epidemiology of thyroid eye disease (TED) in New Zealand.
Methods: One hundred and sixty-one subjects with TED seen over a 14-year period in Auckland, from a combined ophthalmology-endocrinology clinic, had data extracted from clinical notes.
Results: Median age at onset was 47.