Publications by authors named "Liza D van de Groep"
Therapies for inoperable chronic thromboembolic pulmonary hypertension (CTEPH) include balloon pulmonary angioplasty (BPA) and PH-specific medical therapy. This study compares survival and its predictors before and after the introduction of BPA. BPA was independently associated with survival; however, there was no difference in overall survival between the two cohorts.
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- The study assesses the survival rates of pulmonary arterial hypertension (PAH) patients over 15 years, analyzing 293 adults diagnosed between 2005 and 2019.
- The findings reveal that while therapeutic advances have been made, overall transplant-free survival rates (median 6.2 years) did not improve significantly over time, particularly for younger patients.
- Factors such as demographic changes and delays in diagnosis may contribute to the stagnant survival rates despite more treatment options being available.
Background: Multiple biomarkers have been investigated in the risk stratification of patients with pulmonary arterial hypertension (PAH). This systematic review and meta-analysis is the first to investigate the prognostic value of (NT-pro)BNP in patients with PAH.
Methods: A systematic literature search was performed using MEDLINE, Embase, Web of Science, the Cochrane Library and Google scholar to identify studies on the prognostic value of baseline (NT-pro)BNP levels in PAH.