Background: This study examines the anatomical characteristics of the mitral isthmus (MI) and its spatial relationship with the esophagus in patients undergoing atrial fibrillation ablation, using cardiovascular computed tomographic angiography (CTA). Understanding this relationship is crucial to minimize the risk of esophageal injuries during ablation procedures.
Methods: The investigation included 300 participants, divided into 200 subjects in the experimental group undergoing atrial fibrillation ablation and 100 in the control group.
IEEE Trans Pattern Anal Mach Intell
December 2024
We developed a single quantum dot-based fluorescence resonance energy transfer biosensor for antibody-free detection of ten-eleven translocation 1 (TET1). This biosensor can sensitively detect TET1 in a homogeneous manner without the involvement of any specific antibodies, and it can be used for accurate measurement of TET1 activity in human neuroblastoma cells and the screening of TET1 inhibitors.
View Article and Find Full Text PDFSirtuin 1 (SIRT1) is an important histone deacetylase that regulates biological functions ranging from DNA repair to metabolism. The alteration of SIRT1 is associated with a variety of diseases including diabetes, inflammation, aging-related diseases, and cancers. Consequently, the detection of SIRT1 activity is of great therapeutic importance.
View Article and Find Full Text PDFIEEE Trans Pattern Anal Mach Intell
May 2022
Event-based cameras measure intensity changes (called 'events') with microsecond accuracy under high-speed motion and challenging lighting conditions. With the 'active pixel sensor' (APS), the 'Dynamic and Active-pixel Vision Sensor' (DAVIS) allows the simultaneous output of intensity frames and events. However, the output images are captured at a relatively low frame rate and often suffer from motion blur.
View Article and Find Full Text PDFIEEE Trans Image Process
October 2019
Stereo videos for the dynamic scenes often show unpleasant blurred effects due to the camera motion and the multiple moving objects with large depth variations. Given consecutive blurred stereo video frames, we aim to recover the latent clean images, estimate the 3D scene flow and segment the multiple moving objects. These three tasks have been previously addressed separately, which fail to exploit the internal connections among these tasks and cannot achieve optimality.
View Article and Find Full Text PDFEighty-six R1 QTLs accounting for 89.92% phenotypic variance in a soybean RIL population were identified using RTM-GWAS with SNPLDB marker which performed superior over CIM and MLM-GWAS with BIN/SNPLDB marker. A population (NJRIKY) composed of 427 recombinant inbred lines (RILs) derived from Kefeng-1 × NN1138-2 (MGII × MGV, MG maturity group) was applied for detecting flowering date (R1) quantitative trait locus (QTL) system in soybean.
View Article and Find Full Text PDFBackground: Gastric cancer is 2th most common cancer in China, and is still the second most common cause of cancer-related death in the world. Successful development of safe and effective nanoprobes for in vivo gastric cancer targeting imaging is a big challenge. This study is aimed to develop folic acid (FA)-conjugated silica coated gold nanoclusters (AuNCs) for targeted dual-modal fluorescent and X-ray computed tomography imaging (CT) of in vivo gastric cancer cells.
View Article and Find Full Text PDFUpconversion nanocrystals with small size and strong fluorescent signals own great potential in applications such as biomolecule-labeling, in vivo tracking and molecular imaging. Herein we reported that NaYbF4: 25%Gd, 2%Tm upconversion nanocrystals with small size and strong fluorescent signals were controllably synthesized by oleic acid (OA)/ ionic liquid (IL) two-phase system for targeted fluorescent imaging of gastric cancer in vivo. The optimal synthesis condition of NaYbF4: 25%Gd, 2%Tm upconversion nanocrystals by OA/IL two-phase system was established, adding more metal ion such as Na(+) ion could facilitate the size control and crystal-phase transition, more importantly, markedly enhancing fluorescent intensity of beta-phase nanocrystals compared with traditional methods.
View Article and Find Full Text PDFDevelopment of multimodal contrast agents for in vivo simultaneous multimodality imaging is an emerging interdiscipline that is paving the avenue toward the goal of personalized medicine. Herein, folic acid-conjugated silica-modified LaF(3):Yb,Tm upconversion nanoparticles (UCNPs@SiO(2)-FA) with high La content in a single particle were strategically designed and prepared for simultaneously targeting dual-modality imaging of upconversion luminescence (UCL) and X-ray computed tomography (CT). LaF(3) UCNPs were synthesized by a novel oleic acid (OA)/ionic liquid (IL) two-phase system.
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