Publications by authors named "Liyu Kong"
J Extracell Vesicles
September 2024
Article Synopsis
- Reactive oxygen species (ROS) are responsible for damaging DNA, leading to mutations that can cause cancer and tumor growth.
- The study shows that ROS-related DNA damage increases the release of extracellular vesicles (EVs) that enhance cancer cell migration and invasion by promoting epithelial-mesenchymal transition (EMT).
- A key player in this process is OGG1, which, when inhibited, can block EV release, reduce cancer progression, and suggests new therapeutic targets for treating cancer.
