Cervical cancer (CC) is the fourth most common cancer among women worldwide. As part of the brisk cross-talk between the host and the tumor, prognosis can be affected through inflammatory responses or the tumor microenvironment. However, further exploration of the inflammatory response-related genes that have prognostic value, microenvironment infiltration, and chemotherapeutic therapies in CC is needed.
View Article and Find Full Text PDFCervical carcinoma is the most prevalent gynecology malignant tumor and ranks as the fourth most common cancer worldwide, thus posing a significant threat to the lives and health of women. Advanced and early-stage cervical carcinoma patients with high-risk factors require adjuvant treatment following surgery, with radiotherapy being the primary approach. However, the tolerance of cervical cancer to radiotherapy has become a major obstacle in its treatment.
View Article and Find Full Text PDFA ternary hierarchical hybrid Ni@CoS/poly(3,4-ethylenedioxythiophene)-reduced graphene oxide (Ni@CoS/PEDOT-rGO) is rationally designed and in situ facilely synthesized as electrocatalyst to construct a binder-free sensing platform for non-enzymatic glucose monitoring through traditional electrodeposition procedure. The as-prepared Ni@CoS/PEDOT-rGO presents unique hierarchical structure and multiple valence states as well as strong and robust adhesion between Ni@CoS/PEDOT-rGO and GCE. Profiting from the aforementioned merits, the sensing platform constructed under optimal conditions achieved a wide detection range (0.
View Article and Find Full Text PDFThe tumor microenvironment plays a critical role in the radiotherapy and immunotherapy response of cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC). Radioresistance is a key factor in treatment failure among patients who receive radical radiotherapy. Thus, new immune-related biomarkers associated with radiotherapy response in CESC are needed.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
February 2023
The new-energy industry, which is a key area for coping with climate change, faces serious credit-financing difficulties. This study used a bilateral stochastic frontier model to measure the bargaining power of new-energy companies in China's credit-financing market. We then examined the main factors affecting the bargaining power of new-energy enterprises by comparing the results of the firms in different groups, including corporate-related factors, government policies, and financial development levels.
View Article and Find Full Text PDFThe difficulty to achieve rapid detection is the limitation of many enzyme-free sensors today. Thus, designing tri-functionalsensors with ultra-fast and efficientdeterminationis a challenging taskin biological science. Herein, curly fish scales-like NiMoS active materials was anchored on poly (3,4-ethylenedioxythiophene)-reduced graphene oxide (PEDOT-rGO) hybrid membranes with uneven surface (NiMoS/PEDOT-rGO) as a high-performance tri-functional catalyst for glucose, nitrite and hydrogen peroxide determination.
View Article and Find Full Text PDFNickel sulfide nanoworm (NiS NW) network architecture was directly grown on the poly (3,4-ethylenedioxythiophene)-reduced graphene oxide hybrid films (PEDOT-rGO HFs) modified on glassy carbon electrode (GCE), acting as a binder-free sensor for high-performance non-enzymatic glucose monitoring. The sensor exhibited the satisfactory sensitivity (2123 μA mM cm), wide linear range (15~9105 μM), low detection limit (0.48 μM), and rapid response time (< 1.
View Article and Find Full Text PDFAn antifouling aptasensor is described for voltammetric determination of adenosine triphosphate (ATP). A glassy carbon electrode (GCE) was modified with a graphene oxide and poly(3,4-ethylenedioxythiophene) (GO-PEDOT) composite film by electrodeposition. Next, the zwitterionic peptide (EKEKEKE) was attached.
View Article and Find Full Text PDFA facile, controllable two-step electrodeposition synthesis route was developed, whereby a honeycomb-like amorphous cobalt sulfide architecture was obtained via direct growth on a glassy carbon electrode (GCE) functionalized by a reduced graphene oxide-poly(3,4-ethylenedioxythiophene) (rGO-PEDOT) composite film as an electrode for glucose detection. This electrodeposition method is binder-free, rapid, low-cost and preparation-controlled. The effects of the concentration ratio between CoCl·6HO and thiourea, deposition scanning rate and deposition cycles on glucose detection were investigated, and the optimum preparation conditions were determined.
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